Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.57 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SLC40A1 | Q9NP59 | 4/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28384243 | 1.00 | KEAP1 (0.57) | KEAP1NFE2L2GAAPGAM1MEN1 | |
| SCHEMBL30009985 | 0.76 | RXFP1 (0.67) | KEAP1NFE2L2GAAMEN1KMT2A | |
| SCHEMBL13510393 | 0.75 | KEAP1 (0.66) | KEAP1NFE2L2GAAPGAM1MEN1 | |
| SCHEMBL7571584 | 0.74 | SLC40A1 (0.66) | GAAMEN1KMT2AALDH1A1POLB | |
| SCHEMBL13510067 | 0.73 | MEN1 (0.69) | KEAP1NFE2L2GAAMEN1KMT2A | |
| SCHEMBL29540765 | 0.72 | GAA (0.71) | KEAP1NFE2L2GAAMEN1KMT2A | |
| SCHEMBL22234047 | 0.72 | GAA (0.71) | KEAP1NFE2L2GAAMEN1KMT2A | |
| SCHEMBL13509977 | 0.72 | MEN1 (0.81) | KEAP1NFE2L2GAAPGAM1MEN1 | |
| SCHEMBL7569885 | 0.72 | ALDH1A1 (0.59) | GAAMEN1KMT2AALDH1A1POLB | |
| SCHEMBL30009654 | 0.72 | MAPT (0.67) | KEAP1NFE2L2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111067889-B | Application of 2-methyl naphtho [1,2-b ] furan compound in preparation of medicine related to diabetic nephropathy | 徐州医科大学 | 2022-11-18 | — | — | CN | disclosed |