Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 12/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 9/20 | 0.45 |
| ▸ | PDE4A | P27815 | 7/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34462332 | 0.77 | TLR7 (0.36) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL34462323 | 0.74 | ADORA3 (0.43) | ADORA2BADORA3BLM | |
| SCHEMBL30110608 | 0.74 | ADORA2A (0.49) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL20157445 | 0.69 | PDE3B (0.45) | ADORA2BADORA2AHPGDPDE3AGRIN1 | |
| SCHEMBL30323763 | 0.67 | TYRO3 (0.53) | PDE3A | |
| SCHEMBL29837916 | 0.66 | HTR1A (0.44) | PDE3AMAPT | |
| SCHEMBL30141680 | 0.66 | MAT2A (0.37) | HPGDPDE3AHSD17B10GLAMAPT | |
| SCHEMBL23632980 | 0.66 | DYRK1A (0.35) | PDE3AHSD17B10MAPT | |
| SCHEMBL29838035 | 0.66 | DYRK1A (0.35) | PDE3AHSD17B10MAPT | |
| SCHEMBL11227373 | 0.64 | GRIN1 (0.57) | GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4065155-A1 | TLR7 AGONISTS | Primmune Therapeutics, Inc. (US) | 2022-10-05 | — | — | EP | disclosed |