Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 9/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5540980 | 0.87 | VCAM1 (0.59) | ALDH1A1CYP3A4TSHRTDP1MEN1 | |
| SCHEMBL8303947 | 0.83 | ALDH1A1 (0.71) | ALDH1A1CYP3A4TSHRTDP1MEN1 | |
| SCHEMBL15208644 | 0.81 | VCAM1 (0.53) | ALDH1A1CYP3A4TSHRTDP1MEN1 | |
| SCHEMBL288907 | 0.80 | CASP6 (0.64) | TSHRLMNAHCAR3 | |
| SCHEMBL16119726 | 0.80 | WNT3A (0.55) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL6624180 | 0.80 | ALDH1A1 (0.66) | ALDH1A1CYP3A4TSHRTDP1MEN1 | |
| SCHEMBL31546625 | 0.80 | MAPT (0.69) | ALDH1A1CYP3A4TSHRTDP1MEN1 | |
| SCHEMBL6647253 | 0.80 | MEN1 (0.72) | ALDH1A1CYP3A4TSHRTDP1MEN1 | |
| SCHEMBL1455286 | 0.80 | KMT2A (0.90) | ALDH1A1CYP3A4TSHRTDP1MEN1 | |
| SCHEMBL2779018 | 0.80 | KMT2A (0.68) | ALDH1A1CYP3A4TSHRTDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427427-A1 | 4 -CYANO- 3 -BENZOYLAMINO-N- PHENYL-BENZAMIDES FOR USE IN PEST CONTROL | Syngenta Participations AG (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010127926-A1 | 4 -CYANO- 3 -BENZOYLAMINO-N- PHENYL-BENZAMIDES FOR USE IN PEST CONTROL | SYNGENTA PARTICIPATIONS AG (CH) | 2010-11-11 | — | — | WO | disclosed |