Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 7/20 | 0.45 |
| ▸ | CHRM1 known ✓ | P11229 | 7/20 | 0.45 |
| ▸ | CHRM3 known ✓ | P20309 | 7/20 | 0.45 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.54 |
| ▸ | BLM | P54132 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | XBP1 | P17861 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12334555 | 0.89 | PRMT1 (0.56) | PRMT1BLMMEN1NPC1LMNA | |
| SCHEMBL12334547 | 0.88 | PRMT1 (0.57) | PRMT1BLMMEN1NPC1LMNA | |
| SCHEMBL27355880 | 0.88 | PRMT1 (0.53) | PRMT1BLMMEN1NPC1LMNA | |
| SCHEMBL15432754 | 0.88 | PRMT1 (0.53) | PRMT1BLMMEN1NPC1LMNA | |
| SCHEMBL24767157 | 0.87 | PRMT1 (0.56) | PRMT1BLMMEN1NPC1LMNA | |
| Hydrochloric Acid SCHEMBL29461667 | 0.87 | TMEM97 (0.53) | PRMT1BLMMEN1NPC1LMNA | |
| Hydrochloric Acid SCHEMBL29557300 | 0.87 | TMEM97 (0.53) | PRMT1BLMMEN1NPC1LMNA | |
| SCHEMBL13736305 | 0.86 | TMEM97 (0.54) | PRMT1BLMMEN1NPC1LMNA | |
| SCHEMBL21905440 | 0.86 | TMEM97 (0.54) | PRMT1BLMMEN1NPC1LMNA | |
| SCHEMBL21905438 | 0.86 | TMEM97 (0.54) | PRMT1BLMMEN1NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119708613-B | Polymer porous membrane for fluorescent pattern transfer printing and preparation method and application thereof | 四川大学 | 2026-05-19 | — | — | CN | claimed |
| CN-119708613-A | Polymer porous membrane for fluorescent pattern transfer printing and preparation method and application thereof | 四川大学 | 2025-03-28 | — | — | CN | claimed |
| CN-113820298-B | Self-assembled super-quenched gold nanoparticle nano sensor and preparation method and application thereof | 山东师范大学 | 2024-02-13 | — | — | CN | claimed |
| CN-119708613-B | Polymer porous membrane for fluorescent pattern transfer printing and preparation method and application thereof | 四川大学 | 2026-05-19 | — | — | CN | disclosed |
| US-12616656-B2 | Adventitial painting modality of local drug delivery to abate intimal hyperplasia | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2026-05-05 | — | — | US | disclosed |
| CN-119708613-A | Polymer porous membrane for fluorescent pattern transfer printing and preparation method and application thereof | 四川大学 | 2025-03-28 | — | — | CN | disclosed |
| US-20240238198-A1 | AN ADVENTITIAL PAINTING MODALITY OF LOCAL DRUG DELIVERY TO ABATE INTIMAL HYPERPLASIA | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2024-07-18 | — | — | US | disclosed |
| CN-113820298-B | Self-assembled super-quenched gold nanoparticle nano sensor and preparation method and application thereof | 山东师范大学 | 2024-02-13 | — | — | CN | disclosed |
| WO-2022246462-A1 | AN ADVENTITIAL PAINTING MODALITY OF LOCAL DRUG DELIVERY TO ABATE INTIMAL HYPERPLASIA | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2022-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12616656-B2 | Adventitial painting modality of local drug delivery to abate intimal hyperplasia | ADRA1B, ADRB1, ADRB3 | CHRM2 183/4885CHRM1 161/4885CHRM3 338/4885 |
| US-20240238198-A1 | AN ADVENTITIAL PAINTING MODALITY OF LOCAL DRUG DELIVERY TO ABATE INTIMAL HYPERPLASIA | SHMT1, PNISR, CD44 | CHRM2 2593/4885CHRM1 2097/4885CHRM3 2418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.