Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | BPTF | Q12830 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2753214 | 0.80 | — | — | |
| SCHEMBL27634381 | 0.76 | COMT (0.46) | FAAHMGLLALDH1A1 | |
| SCHEMBL27497687 | 0.76 | NOTUM (0.35) | MGLLMAPTALDH1A1NOTUMMEN1 | |
| SCHEMBL1896817 | 0.76 | CYP3A4 (0.40) | MGLLL3MBTL1MEN1KMT2A | |
| SCHEMBL7536022 | 0.76 | MAPT (0.56) | KEAP1FAAHMGLLMAPTALDH1A1 | |
| SCHEMBL2750984 | 0.72 | ALDH1A1 (0.34) | ALDH1A1L3MBTL1 | |
| SCHEMBL27593451 | 0.70 | FAAH (0.46) | KEAP1FAAHMGLLMAPTALDH1A1 | |
| SCHEMBL1893443 | 0.69 | KEAP1 (0.41) | KEAP1FAAHMGLLMAPTALDH1A1 | |
| SCHEMBL12841352 | 0.68 | KEAP1 (0.52) | KEAP1FAAHMGLLMAPTALDH1A1 | |
| SCHEMBL300545 | 0.68 | KEAP1 (0.43) | KEAP1FAAHMGLLBPTFMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004443-A8 | PHENYL METHYL SULFONES WITH ANTI-INFLAMMATORY ACTIVITY AND ANTI-TUMOUR ACTIVITY | UNIVERSITAT DE BARCELONA (ES) | 2012-02-09 | — | — | WO | disclosed |
| WO-2012004443-A1 | PHENYL METHYL SULFONES WITH ANTI-INFLAMMATORY ACTIVITY AND ANTI-TUMOUR ACTIVITY | UNIVERSITAT DE BARCELONA (ES) | 2012-01-12 | — | — | WO | disclosed |