Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | AOC2 | O75106 | 2/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20319187 | 0.82 | MAPT (0.68) | MAPTFAAHMGLLL3MBTL1ALDH1A1 | |
| SCHEMBL12841352 | 0.77 | KEAP1 (0.52) | MAPTFAAHMGLLKEAP1L3MBTL1 | |
| SCHEMBL9337373 | 0.77 | MAPT (0.39) | MAPTFAAHMGLLKEAP1L3MBTL1 | |
| SCHEMBL1434069 | 0.76 | FAAH (0.46) | MAPTFAAHMGLLKEAP1L3MBTL1 | |
| SCHEMBL870900 | 0.76 | IDO1 (0.64) | MAPTKEAP1MEN1KMT2A | |
| SCHEMBL300208 | 0.76 | KEAP1 (0.42) | MAPTFAAHMGLLKEAP1L3MBTL1 | |
| SCHEMBL28222405 | 0.76 | MGLL (0.46) | MAPTFAAHMGLLKEAP1L3MBTL1 | |
| SCHEMBL13672252 | 0.73 | FAAH (0.52) | MAPTFAAHMGLLKEAP1L3MBTL1 | |
| SCHEMBL2239811 | 0.72 | ALDH1A1 (0.56) | MAPTMGLLL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL10373948 | 0.71 | BPTF (0.54) | MAPTFAAHMGLLALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104418788-A | 1-(3-fluorophenyl)pyrrole and preparation method thereof | TIANJIN HEOWNS BIOCHEMISTRY TECHNOLOGY CO LTD | 2015-03-18 | — | — | CN | claimed |
| WO-2002000623-A2 | ARYL FUSED SUBSTITUTED 4-OXY-PYRIDINES | NEUROGEN CORPORATION (US) | 2002-01-03 | — | — | WO | claimed |
| EP-4157844-B1 | 4-(7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)-3,6-DIHYDROPYRIDINE-1-(2H)-CARBOXAMIDE DERIVATIVES AS LIMK AND/OR ROCK KINASES INHIBITORS FOR USE IN THE TREATMENT OF CANCER | CENTRE NAT RECH SCIENT (FR) | 2024-07-10 | — | — | EP | disclosed |
| CN-104245689-B | Terazololine-one compound and its purposes as insecticide | 住友化学株式会社 | 2017-06-06 | — | — | CN | disclosed |
| EP-3068758-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | The Wistar Institute Of Anatomy And Biology (US) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015073864-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | THE WISAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2015-05-21 | — | — | WO | disclosed |
| CN-104418788-A | 1-(3-fluorophenyl)pyrrole and preparation method thereof | TIANJIN HEOWNS BIOCHEMISTRY TECHNOLOGY CO LTD | 2015-03-18 | — | — | CN | disclosed |
| CN-104418788-A | 1-(3-fluorophenyl)pyrrole and preparation method thereof | TIANJIN HEOWNS BIOCHEMISTRY TECHNOLOGY CO LTD | 2015-03-18 | — | — | CN | disclosed |
| CN-104418788-A | 1-(3-fluorophenyl)pyrrole and preparation method thereof | TIANJIN HEOWNS BIOCHEMISTRY TECHNOLOGY CO LTD | 2015-03-18 | — | — | CN | disclosed |
| WO-2002000623-A2 | ARYL FUSED SUBSTITUTED 4-OXY-PYRIDINES | NEUROGEN CORPORATION (US) | 2002-01-03 | — | — | WO | disclosed |