Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | BPTF | Q12830 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PI4KA | P42356 | 1/20 | 0.36 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.36 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MPI | P34949 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11574910 | 0.77 | MGLL (0.44) | MGLLALDH1A1MAPTNOTUMMEN1 | |
| SCHEMBL8634060 | 0.77 | NOTUM (0.47) | ALDH1A1MAPTNOTUMMEN1KMT2A | |
| SCHEMBL27629824 | 0.73 | PRMT6 (0.41) | ALDH1A1 | |
| SCHEMBL9763868 | 0.70 | KEAP1 (0.49) | KEAP1FAAHMGLLALDH1A1POLB | |
| SCHEMBL28036187 | 0.70 | KEAP1 (0.41) | KEAP1FAAHMGLLBPTFALDH1A1 | |
| SCHEMBL7536022 | 0.69 | MAPT (0.56) | KEAP1FAAHMGLLALDH1A1POLB | |
| SCHEMBL300208 | 0.68 | KEAP1 (0.42) | KEAP1FAAHMGLLBPTFALDH1A1 | |
| SCHEMBL2342193 | 0.67 | KEAP1 (0.53) | KEAP1FAAHMGLLBPTFALDH1A1 | |
| SCHEMBL1975063 | 0.67 | KEAP1 (0.45) | KEAP1FAAHMGLLBPTFALDH1A1 | |
| SCHEMBL16720346 | 0.65 | HPGDS (0.39) | KEAP1FAAHMGLLBPTFALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004443-A8 | PHENYL METHYL SULFONES WITH ANTI-INFLAMMATORY ACTIVITY AND ANTI-TUMOUR ACTIVITY | UNIVERSITAT DE BARCELONA (ES) | 2012-02-09 | — | — | WO | disclosed |
| WO-2012004443-A1 | PHENYL METHYL SULFONES WITH ANTI-INFLAMMATORY ACTIVITY AND ANTI-TUMOUR ACTIVITY | UNIVERSITAT DE BARCELONA (ES) | 2012-01-12 | — | — | WO | disclosed |