Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 2/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | EPRS1 | P07814 | 1/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28668413 | 0.88 | MEN1 (0.47) | PTGS2MEN1KMT2AHSP90AA1KDM4E | |
| SCHEMBL30023487 | 0.87 | DHODH (0.45) | PTGS2ANO1GPR35MAPTSMN1; SMN2 | |
| SCHEMBL30022887 | 0.85 | ALDH1A1 (0.50) | GPR35KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL30023062 | 0.84 | MAPT (0.46) | PTGS2ANO1GPR35KDM4EPTPN1 | |
| SCHEMBL30020913 | 0.83 | MAPT (0.48) | MEN1KMT2AKDM4EGLANPC1 | |
| SCHEMBL30022919 | 0.81 | PTPN22 (0.50) | PTPN1 | |
| SCHEMBL30023383 | 0.81 | RARB (0.46) | MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL28659185 | 0.81 | MEN1 (0.48) | MEN1KMT2AHSP90AA1KDM4EPTPN1 | |
| SCHEMBL28680766 | 0.80 | KDM4E (0.45) | ANO1GPR35MEN1KMT2AKDM4E | |
| SCHEMBL30023247 | 0.80 | KDM4E (0.45) | ANO1GPR35MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113754619-B | Method for preparing polysubstituted benzofuran-4-formic acid compound under catalysis of ruthenium | 广州大学 | 2022-12-20 | — | — | CN | disclosed |