Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN22 | Q9Y2R2 | 8/20 | 0.50 |
| ▸ | PTPRC | P08575 | 3/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | PTPN6 | P29350 | 3/20 | 0.46 |
| ▸ | PTPN9 | P43378 | 3/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 3/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.46 |
| ▸ | EPM2A | O95278 | 1/20 | 0.44 |
| ▸ | PTPRG | P23470 | 1/20 | 0.44 |
| ▸ | ACP1 | P24666 | 1/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.44 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.44 |
| ▸ | DUSP22 | Q9NRW4 | 1/20 | 0.44 |
| ▸ | CDC14A | Q9UNH5 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30022887 | 0.86 | ALDH1A1 (0.50) | — | |
| SCHEMBL30023062 | 0.85 | MAPT (0.46) | PTPN22PTPRCPTPN2PTPN1PTPN6 | |
| SCHEMBL30023487 | 0.83 | DHODH (0.45) | DHODH | |
| SCHEMBL28668413 | 0.81 | MEN1 (0.47) | PTPN22PTPRCPTPN2PTPN1PTPN6 | |
| SCHEMBL30020913 | 0.81 | MAPT (0.48) | — | |
| SCHEMBL28677868 | 0.81 | KDM4E (0.45) | AKR1C2 | |
| SCHEMBL30023247 | 0.81 | KDM4E (0.45) | AKR1C2 | |
| SCHEMBL28680766 | 0.81 | KDM4E (0.45) | AKR1C2 | |
| SCHEMBL30023283 | 0.81 | KDM4E (0.45) | AKR1C2 | |
| SCHEMBL30022975 | 0.81 | PTGS2 (0.41) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113754619-B | Method for preparing polysubstituted benzofuran-4-formic acid compound under catalysis of ruthenium | 广州大学 | 2022-12-20 | — | — | CN | disclosed |