Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 4/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.41 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28668413 | 0.88 | MEN1 (0.47) | DHODHPTGS2ABCB1SMN1; SMN2MAPT | |
| SCHEMBL30022975 | 0.87 | PTGS2 (0.41) | PTGS2ANO1GPR35SMN1; SMN2MAPT | |
| SCHEMBL30023062 | 0.86 | MAPT (0.46) | PTGS2ANO1GPR35MAPT | |
| SCHEMBL30022887 | 0.85 | ALDH1A1 (0.50) | ABCB1GPR35SMN1; SMN2MAPT | |
| SCHEMBL30022919 | 0.83 | PTPN22 (0.50) | DHODH | |
| SCHEMBL30020913 | 0.83 | MAPT (0.48) | SMN1; SMN2MAPT | |
| SCHEMBL30023383 | 0.81 | RARB (0.46) | DHODHABCB1MAPT | |
| SCHEMBL30023247 | 0.80 | KDM4E (0.45) | ANO1ABCB1GPR35SMN1; SMN2MAPT | |
| SCHEMBL28677868 | 0.80 | KDM4E (0.45) | ANO1ABCB1GPR35SMN1; SMN2MAPT | |
| SCHEMBL30023283 | 0.80 | KDM4E (0.45) | ANO1ABCB1GPR35SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113754619-B | Method for preparing polysubstituted benzofuran-4-formic acid compound under catalysis of ruthenium | 广州大学 | 2022-12-20 | — | — | CN | disclosed |