Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | DAO | P14920 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | DDO | Q99489 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6257336 | 1.00 | AOC3 (0.52) | AOC3CA2NPC1RAB9ALOXL2 | |
| Hydrochloric Acid SCHEMBL5073488 | 0.85 | LOXL2 (0.41) | AOC3CA2NPC1RAB9ALOXL2 | |
| Indene SCHEMBL6628425 | 0.79 | CA2 (0.36) | AOC3CA2NPC1RAB9ALOXL2 | |
| SCHEMBL29631691 | 0.72 | RAB9A (0.74) | AOC3CA2NPC1RAB9ALOXL2 | |
| SCHEMBL374022 | 0.72 | RAB9A (0.74) | AOC3CA2NPC1RAB9ALOXL2 | |
| Hydrochloric Acid SCHEMBL30028254 | 0.71 | AOC3 (0.52) | AOC3CA2NPC1RAB9ALOXL2 | |
| Hydrochloric Acid SCHEMBL30577223 | 0.71 | AOC3 (0.52) | AOC3CA2NPC1RAB9ALOXL2 | |
| Hydrochloric Acid SCHEMBL8460080 | 0.71 | AOC3 (0.52) | AOC3CA2NPC1RAB9ALOXL2 | |
| Hydrochloric Acid SCHEMBL8595187 | 0.71 | AOC3 (0.52) | AOC3CA2NPC1RAB9ALOXL2 | |
| SCHEMBL29377234 | 0.70 | AOC3 (0.56) | AOC3CA2NPC1RAB9ALOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024225868-A1 | METALLOCENE COMPOUND, PRECURSOR THEREOF, AND METHOD FOR PREPARING SAME | 한화솔루션 주식회사 | 2024-10-31 | — | — | WO | disclosed |
| CN-115400797-A | Heteroatom-containing metallocene catalyst system and method for catalyzing alpha-olefin oligomerization | 中国科学院山西煤炭化学研究所 | 2022-11-29 | — | — | CN | disclosed |