SCHEMBL30028871

SCHEMBL30028871

[C-]#[N+]Cc1ccc(-c2ccc(C[N+]#[C-])cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 6/20 0.41
TAAR1 Q96RJ0 3/20 0.35
MAOB P27338 2/20 0.34
IDO1 P14902 2/20 0.31
AGXT P21549 2/20 0.31
ABCC4 O15439 1/20 0.31
LMNA P02545 1/20 0.31
GAA P10253 1/20 0.31
TSHR P16473 1/20 0.31
PTGS1 P23219 1/20 0.31
HTT P42858 1/20 0.31
HRH4 Q9H3N8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5672968 0.80 IDO1 (0.48) TAAR1MAOBIDO1AGXTLMNA
SCHEMBL12374395 0.78 ALDH1A1 (0.50) MAOBTSHR
SCHEMBL4890253 0.78 IDO1 (0.46) HRH3TAAR1IDO1AGXTLMNA
SCHEMBL3890376 0.78 TAAR1 (0.42) TAAR1IDO1
SCHEMBL168131 0.77
SCHEMBL3896151 0.72
SCHEMBL12445232 0.72 ALDH1A1 (0.50) TSHR
SCHEMBL8099830 0.71 MAOA (0.45) TAAR1MAOB
SCHEMBL407367 0.69 DHFR (0.39) TAAR1MAOBLMNA
SCHEMBL12339115 0.66 CYP1A2 (0.54) HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115260835-A High-refractive-index ink based on symmetric thioamide structure and preparation method thereof 西安思摩威新材料有限公司 2022-11-01 CN disclosed