Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPEPPS | P55786 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30032902 | 0.83 | HSP90AA1 (0.48) | NPEPPSHSP90AA1KDM4EHTTMEN1 | |
| SCHEMBL30032796 | 0.82 | CYP11B2 (0.46) | NPEPPSHSP90AA1KDM4EHTTMALT1 | |
| SCHEMBL30033311 | 0.81 | NPEPPS (0.36) | NPEPPSHSP90AA1KDM4EHTTMALT1 | |
| SCHEMBL30033551 | 0.81 | ALDH1A1 (0.40) | NPEPPSHSP90AA1KDM4EHTTMALT1 | |
| SCHEMBL31509793 | 0.80 | NPEPPS (0.57) | NPEPPSKDM4EHTTCYP11B1CYP11B2 | |
| SCHEMBL30034350 | 0.80 | NPEPPS (0.42) | NPEPPSHSP90AA1KDM4EHTTPKM | |
| SCHEMBL30033459 | 0.79 | PKM (0.43) | NPEPPSHSP90AA1KDM4EHTTCYP11B1 | |
| SCHEMBL30033336 | 0.78 | GRIN1 (0.39) | HSP90AA1MALT1 | |
| SCHEMBL30033042 | 0.77 | KDM4E (0.57) | NPEPPSKDM4EHTTPKMHSD17B10 | |
| SCHEMBL30032168 | 0.77 | NPEPPS (0.49) | NPEPPSKDM4EHTTPKMHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022224223-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CORONAVIRAL RELATED DISEASES | NOVARTIS AG (CH) | 2022-10-27 | — | — | WO | disclosed |