SCHEMBL3004307

SCHEMBL3004307

CCCCCCCC(=O)OCC(=O)COC(=O)CCCCCCC

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PAM P19021 2/20 0.74
DGKA P23743 1/20 0.69
TSHR P16473 1/20 0.58
MAPT P10636 1/20 0.58
LMNA P02545 4/20 0.56
DNM1 Q05193 1/20 0.56
ALDH1A1 P00352 1/20 0.56
KDM4E B2RXH2 1/20 0.55
DUSP3 P51452 1/20 0.55
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
PRSS1 P07477 1/20 0.53
PRSS2 P07478 1/20 0.53
PRSS3 P35030 1/20 0.53
PRKCA P17252 1/20 0.51
PRKCE Q02156 1/20 0.51
PRKCQ Q04759 1/20 0.51
PRKCD Q05655 1/20 0.51
CES2 O00748 3/20 0.50
CES1 P23141 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8041026 1.00 PAM (0.74) PAMDGKATSHRMAPTLMNA
SCHEMBL19940077 1.00 PAM (0.74) PAMDGKATSHRMAPTLMNA
SCHEMBL3924509 1.00 PAM (0.74) PAMDGKATSHRMAPTLMNA
SCHEMBL19944379 1.00 PAM (0.74) PAMDGKATSHRMAPTLMNA
SCHEMBL1901901 1.00 PAM (0.74) PAMDGKATSHRMAPTLMNA
SCHEMBL17237693 1.00 PAM (0.74) PAMDGKATSHRMAPTLMNA
SCHEMBL19912168 0.94 PAM (0.71) PAMDGKATSHRMAPTLMNA
SCHEMBL22077717 0.92 DGKA (0.71) PAMDGKATSHRMAPTLMNA
SCHEMBL22078522 0.92 DGKA (0.71) PAMDGKATSHRMAPTLMNA
SCHEMBL9912287 0.92 PAM (0.65) PAMDGKATSHRMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240391870-A1 IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY ARCTURUS THERAPEUTICS, INC. 2024-11-28 US disclosed
EP-4430026-A1 IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY Arcturus Therapeutics, Inc. (US) 2024-09-18 EP disclosed
US-11903992-B2 Composition comprising lidocaine, l-carnosine and dexpanthenol CELLIX BIO PRIVATE LIMITED (IN) 2024-02-20 US disclosed
WO-2023187664-A1 A PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF IMMUNE SYSTEM MEDIATED DISEASES AVACA PHARMA PRIVATE LIMITED (IN) 2023-10-05 WO disclosed
US-20230295081-A1 IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY ARCTURUS THERAPEUTICS, INC. 2023-09-21 US disclosed
US-20230295081-A1 IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY ARCTURUS THERAPEUTICS, INC. 2023-09-21 US disclosed
US-20230295081-A1 IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY ARCTURUS THERAPEUTICS, INC. 2023-09-21 US disclosed
EP-4230619-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF FUNGAL INFECTIONS CELLIX BIO PRIVATE LIMITED (IN) 2023-08-23 EP disclosed
WO-2023086514-A1 IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY ARCTURUS THERAPEUTICS, INC. (US) 2023-05-19 WO disclosed
WO-2023086514-A1 IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY ARCTURUS THERAPEUTICS, INC. (US) 2023-05-19 WO disclosed
EP-3538079-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF ORAL INFECTIOUS DISEASES CELLIX BIO PRIVATE LIMITED (IN) 2019-09-18 EP disclosed
WO-2018122626-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF CHRONIC PAIN CELLIX BIO PRIVATE LIMITED (IN) 2018-07-05 WO disclosed
WO-2018096405-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF ORAL INFECTIOUS DISEASES CELLIX BIO PRIVATE LIMITED (IN) 2018-05-31 WO disclosed
WO-2018096497-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF FUNGAL INFECTIONS CELLIX BIO PRIVATE LIMITED (IN) 2018-05-31 WO disclosed
US-8236854-B2 Lipid-improving agent and composition containing lipid-improving agent SUNTORY HOLDINGS LIMITED (JP) 2012-08-07 US disclosed
US-20100190857-A1 LIPID-IMPROVING AGENT AND COMPOSITION CONTAINING LIPID-IMPROVING AGENT SUNTORY HOLDINGS LIMITED (JP) 2010-07-29 US disclosed
US-7723386-B2 Lipid-improving agent and composition containing lipid-improving agent SUNTORY HOLDINGS LIMITED (JP) 2010-05-25 US disclosed
US-20060217441-A1 Lipid-improving agent and composition containing lipid-improving agent SUNTORY LIMITED (JP) 2006-09-28 US disclosed
EP-1605768-A2 LIPID-IMPROVING AGENT AND COMPOSITION CONTAINING LIPID-IMPROVIMG AGENT SUNTORY LIMITED (JP) 2005-12-21 EP disclosed
WO-2004085582-A2 LIPID-IMPROVING AGENT AND COMPOSITION CONTAINING LIPID-IMPROVING AGENT SUNTORY LIMITED (JP) 2004-10-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240391870-A1 IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY NSUN3, POLRMT, NPC1L1 PAM 3398/4885DGKA 807/4885TSHR 1676/4885
US-20230295081-A1 IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY NSUN3, POLRMT, NPC1L1 PAM 3398/4885DGKA 807/4885TSHR 1676/4885
US-11903992-B2 Composition comprising lidocaine, l-carnosine and dexpanthenol VNN1, LPL, HMGB1 PAM 1070/4885DGKA 1522/4885TSHR 4877/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.