Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465706 | 1.00 | ALDH1A1 (0.56) | ALDH1A1KMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL28806287 | 0.86 | BRD4 (0.43) | ALDH1A1KMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL18405111 | 0.83 | KDM4E (0.45) | ALDH1A1KMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL14822759 | 0.81 | RIPK1 (0.44) | ALDH1A1KMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL14822757 | 0.81 | CYP3A4 (0.48) | ALDH1A1KMT2AMEN1MAPTCYP19A1 | |
| SCHEMBL27407526 | 0.79 | BRD4 (0.46) | ALDH1A1KMT2AMEN1MAPTBRD4 | |
| SCHEMBL3809851 | 0.78 | TP53 (0.45) | MAPTBRD4CYP3A4CYP2C9GAA | |
| SCHEMBL1953678 | 0.78 | BRD4 (0.43) | KMT2AMEN1MAPTBRD4CYP1A2 | |
| SCHEMBL2202098 | 0.78 | GAA (0.50) | KMT2AMEN1MAPTL3MBTL1CYP19A1 | |
| SCHEMBL30364150 | 0.78 | GAA (0.50) | KMT2AMEN1MAPTL3MBTL1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117064860-A | Preparation method of riocigua tablet | 北京云鹏鹏程医药科技有限公司 | 2023-11-17 | — | — | CN | disclosed |
| US-11491153-B2 | Methods for treating cancer using pyrimidine and pyridine compounds with BTK inhibitory activity | MERCK PATENT GMBH (DE) | 2022-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11491153-B2 | Methods for treating cancer using pyrimidine and pyridine compounds with BTK inhibitory activity | BTK, SYK, LCK | ALDH1A1 3107/4885KMT2A 1280/4885MEN1 3993/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.