Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MPO | P05164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465706 | 0.83 | ALDH1A1 (0.56) | KDM4EALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL30047375 | 0.83 | ALDH1A1 (0.56) | KDM4EALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL25376082 | 0.78 | MEN1 (0.45) | MPOMEN1KMT2AMAPTPKM | |
| SCHEMBL6071681 | 0.74 | MPO (0.60) | KDM4EMPOALDH1A1MEN1KMT2A | |
| SCHEMBL7771685 | 0.74 | FDPS (0.41) | MEN1KMT2AMAPTLMNAGAA | |
| Benzylamine SCHEMBL25375530 | 0.72 | LMNA (0.43) | MEN1KMT2AMAPTLMNAGAA | |
| SCHEMBL631227 | 0.71 | MPO (0.58) | MPOALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL28806287 | 0.70 | BRD4 (0.43) | ALDH1A1MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL18899150 | 0.70 | ALDH1A1 (0.64) | KDM4EMPOALDH1A1MEN1KMT2A | |
| SCHEMBL21674321 | 0.68 | MPO (0.59) | MPOMEN1KMT2ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588465-B1 | SGC STIMULATORS | IRONWOOD PHARMACEUTICALS INC (US) | 2017-01-25 | — | — | EP | disclosed |