Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 6/20 | 0.39 |
| ▸ | CNR2 | P34972 | 8/20 | 0.39 |
| ▸ | MARS1 | P56192 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL176655 | 0.88 | CNR1 (0.49) | LPAR5CNR1CNR2 | |
| SCHEMBL300710 | 0.83 | CNR2 (0.46) | CNR1CNR2 | |
| SCHEMBL300472 | 0.77 | PDE9A (0.38) | — | |
| SCHEMBL300468 | 0.77 | FAAH (0.44) | CNR1CNR2 | |
| SCHEMBL300711 | 0.76 | CNR2 (0.44) | CNR1CNR2 | |
| SCHEMBL300388 | 0.76 | CNR2 (0.46) | CNR1CNR2 | |
| SCHEMBL300475 | 0.76 | CNR2 (0.42) | CNR1CNR2 | |
| SCHEMBL14089543 | 0.75 | CNR2 (0.49) | CNR1CNR2 | |
| SCHEMBL300372 | 0.75 | CNR2 (0.42) | CNR1CNR2 | |
| SCHEMBL300689 | 0.74 | CNR1 (0.40) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937259-B1 | HEXAHYDRO-CYCLOHEPTAPYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-11-23 | — | — | EP | claimed |