Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL176489 | 0.85 | ALDH1A1 (0.43) | GLAALDH1A1TSHRKDM4EMEN1 | |
| SCHEMBL4213055 | 0.78 | MEN1 (0.39) | ALDH1A1MEN1KMT2A | |
| SCHEMBL300734 | 0.78 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1 | |
| SCHEMBL300713 | 0.77 | CNR2 (0.44) | ALDH1A1CCR3TSHRKDM4EMEN1 | |
| SCHEMBL300472 | 0.76 | PDE9A (0.38) | CCR3POLBRAB9A | |
| SCHEMBL300469 | 0.72 | CYP3A4 (0.40) | ALDH1A1KDM4E | |
| SCHEMBL176706 | 0.71 | THRB (0.47) | ALDH1A1KDM4EMEN1NPC1POLB | |
| SCHEMBL300693 | 0.70 | CNR1 (0.40) | CCR3POLB | |
| SCHEMBL300521 | 0.70 | CNR2 (0.43) | — | |
| SCHEMBL176551 | 0.69 | CNR2 (0.54) | ALDH1A1TSHRKDM4EMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937259-B1 | HEXAHYDRO-CYCLOHEPTAPYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-11-23 | — | — | EP | claimed |