Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | BRD2 | P25440 | 1/20 | 0.40 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.40 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31387068 | 0.85 | BRD4 (0.42) | LMNABRD4CNR2CNR1KDM4E | |
| SCHEMBL9852009 | 0.72 | BRD4 (0.44) | LMNAMAPTBRD4BRD2BRD3 | |
| SCHEMBL31328978 | 0.72 | PKM (0.46) | MAPTBRD4KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL11354910 | 0.70 | ALDH1A1 (0.46) | LMNAMAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9772531 | 0.68 | PKM (0.48) | LMNAMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL31328905 | 0.68 | PKM (0.48) | LMNAMAPTALDH1A1CA12CA1 | |
| SCHEMBL12881525 | 0.68 | RAB9A (0.56) | MAPTKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL17492751 | 0.67 | POLB (0.42) | LMNAKDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL28043502 | 0.66 | MAPT (0.43) | LMNAMAPTBRD4BRD2BRD3 | |
| SCHEMBL9772614 | 0.65 | PKM (0.44) | LMNAMAPTCNR2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112574230-B | Peptidyl arginine deiminase inhibitors and uses thereof | 药捷安康(南京)科技股份有限公司 | 2022-10-28 | — | — | CN | disclosed |