Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | BRD2 | P25440 | 1/20 | 0.44 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.44 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5508305 | 0.81 | PARP1 (0.46) | PARP1ESR1MAPTLMNAMEN1 | |
| SCHEMBL9037906 | 0.76 | NPC1 (0.48) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL17234166 | 0.75 | PARP1 (0.49) | PARP1ESR1MAPTLMNAMEN1 | |
| SCHEMBL9037774 | 0.74 | NPSR1 (0.47) | LMNAALDH1A1NPC1RAB9ACNR2 | |
| SCHEMBL12881525 | 0.73 | RAB9A (0.56) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL6993812 | 0.72 | NPC1 (0.47) | BRD4MAPTLMNAMEN1KMT2A | |
| SCHEMBL30065638 | 0.72 | LMNA (0.42) | BRD4BRD2BRD3BRDTMAPT | |
| SCHEMBL28345767 | 0.71 | FABP4 (0.45) | PARP1MAPTLMNAMEN1KMT2A | |
| SCHEMBL1389098 | 0.71 | KDM1A (0.46) | BRD4MAPTMEN1KMT2ANPC1 | |
| SCHEMBL7390566 | 0.70 | PARP1 (0.54) | PARP1ESR1MAPTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0441349-A1 | Pyrroloazepine derivatives | SUNTORY LIMITED (JP) | 1991-08-14 | — | — | EP | disclosed |