Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 5/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | PRKCB | P05771 | 1/20 | 0.38 |
| ▸ | GRK2 | P25098 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | GRK5 | P34947 | 1/20 | 0.38 |
| ▸ | GRK6 | P43250 | 1/20 | 0.38 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.38 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.38 |
| ▸ | GRK7 | Q8WTQ7 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30071914 | 0.85 | CYP11B2 (0.51) | ROCK2ROCK1TP53KDM4EGAA | |
| SCHEMBL30071733 | 0.81 | CYP11B1 (0.48) | KDM4ECYP11B2 | |
| SCHEMBL30072144 | 0.78 | DBH (0.41) | ROCK2KDM4EGRIN1GRIN2B | |
| SCHEMBL30072152 | 0.75 | TP53 (0.50) | TP53KDM4ECYP11B2 | |
| SCHEMBL30595217 | 0.74 | PARN (0.54) | RXFP1GAACYP11B2 | |
| SCHEMBL30320602 | 0.74 | DUT (0.50) | ROCK2TP53MTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL30071806 | 0.73 | BRD4 (0.49) | TP53P2RX3GAAL3MBTL1CYP11B2 | |
| SCHEMBL30072048 | 0.72 | CYP11B2 (0.46) | KDM4EGAACYP11B2 | |
| SCHEMBL30072054 | 0.72 | CYP11B2 (0.46) | KDM4EGAACYP11B2 | |
| SCHEMBL11098685 | 0.71 | ADORA2A (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12221424-B2 | 3-tetrazolylmethyl-1,3,5-triazin-2,4-dione compound inhibiting coronavirus 3CL protease activity and preparation method and use thereof | Shaanxi Panlong Pharmaceutical Co., Ltd. (CN) | 2025-02-11 | — | — | US | disclosed |
| CN-115260167-B | 3-Tetrazolylmethyl-1, 3, 5-triazine-2, 4-dione compound and preparation method and application thereof | 陕西盘龙药业集团股份有限公司 | 2025-01-21 | — | — | CN | disclosed |
| CN-117186077-A | 3-triazolylmethyl-1, 3, 5-triazine-2, 4-dione compound and preparation method and application thereof | 陕西盘龙药业集团股份有限公司 | 2023-12-08 | — | — | CN | disclosed |
| US-20230391736-A1 | 3-TETRAZOLYLMETHYL-1,3,5-TRIAZIN-2,4-DIONE COMPOUND INHIBITING CORONAVIRUS 3CL PROTEASE ACTIVITY AND PREPARATION METHOD AND USE THEREOF | Shaanxi Panlong Pharmaceutical Co., Ltd. (CN) | 2023-12-07 | — | — | US | disclosed |
| US-11612603-B1 | 3-triazolyl methyl-1,3,5-triazine-2,4-dione compounds and preparation method and application thereof | Shaanxi Panlong Pharmaceutical Co., Ltd. (CN) | 2023-03-28 | — | — | US | disclosed |
| CN-115260167-A | 3-tetrazolylmethyl-1, 3, 5-triazine-2, 4-diketone compound and preparation method and application thereof | 陕西盘龙药业集团股份有限公司 | 2022-11-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11612603-B1 | 3-triazolyl methyl-1,3,5-triazine-2,4-dione compounds and preparation method and application thereof | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, TERT, TAAR5 | ROCK2 661/4885ROCK1 440/4885TP53 2907/4885 |
| US-12221424-B2 | 3-tetrazolylmethyl-1,3,5-triazin-2,4-dione compound inhibiting coronavirus 3CL protease activity and preparation method and use thereof | ACE2, ACE, GTF3C3 | ROCK2 2464/4885ROCK1 2622/4885TP53 2519/4885 |
| US-20230391736-A1 | 3-TETRAZOLYLMETHYL-1,3,5-TRIAZIN-2,4-DIONE COMPOUND INHIBITING CORONAVIRUS 3CL PROTEASE ACTIVITY AND PREPARATION METHOD AND USE THEREOF | ACE2, ACE, GTF3C3 | ROCK2 2464/4885ROCK1 2622/4885TP53 2519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.