Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 5/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | LPO | P22079 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7759057 | 0.86 | MAPT (0.57) | DUTMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL7255021 | 0.81 | PKM (0.46) | DUTMAPTALDH1A1PKMLMNA | |
| SCHEMBL20334334 | 0.76 | MAPT (0.58) | DUTMAPTMEN1KMT2APKM | |
| SCHEMBL20333609 | 0.76 | PKM (0.51) | DUTPKML3MBTL1CRBN | |
| SCHEMBL2800300 | 0.75 | DUT (0.59) | DUTALDH1A1CRBN | |
| SCHEMBL30072025 | 0.74 | ROCK2 (0.46) | MTNR1AMTNR1BTP53L3MBTL1ROCK2 | |
| SCHEMBL19370631 | 0.74 | DAO (0.50) | DUTMTNR1AMTNR1BMAPTMEN1 | |
| SCHEMBL29777943 | 0.73 | L3MBTL1 (0.60) | DUTMAPTALDH1A1KMT2APKM | |
| SCHEMBL26043869 | 0.73 | DUT (0.49) | DUTPKML3MBTL1CRBN | |
| SCHEMBL19370625 | 0.72 | DUT (0.50) | DUTALDH1A1PKMLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115785080-B | Uracil parent nucleus compound and preparation method and application thereof | 陕西盘龙药业集团股份有限公司 | 2024-10-11 | — | — | CN | disclosed |
| CN-115785080-A | Uracil parent nucleus compound and preparation method and application thereof | 陕西盘龙药业集团股份有限公司 | 2023-03-14 | — | — | CN | disclosed |