Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2959432 | 0.86 | CHRM4 (0.52) | LMNAMAPTKMT2AHDAC3HDAC4 | |
| SCHEMBL30080392 | 0.85 | PKM (0.60) | LMNAKMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL30080684 | 0.84 | POLB (0.60) | CNR1KMT2APOLBATMKDM4E | |
| SCHEMBL30080500 | 0.80 | NR1H4 (0.58) | NR1H4CNR1LMNAMAPTKMT2A | |
| SCHEMBL28919025 | 0.80 | NR1H4 (0.58) | NR1H4CNR1LMNAMAPTKMT2A | |
| SCHEMBL8048603 | 0.79 | ALDH1A1 (0.61) | KMT2APOLBENPP2ALDH1A1USP2 | |
| SCHEMBL2953334 | 0.78 | ALDH1A1 (0.56) | CNR1LMNAKMT2APOLBKDM4E | |
| SCHEMBL28919039 | 0.77 | CNR1 (0.53) | NR1H4CNR1LMNAMAPTKMT2A | |
| SCHEMBL30080374 | 0.76 | NR1H4 (0.54) | NR1H4CNR1MAPTHDAC3HDAC4 | |
| SCHEMBL28919042 | 0.76 | NR1H4 (0.54) | NR1H4CNR1MAPTHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115521272-B | Benzenesulfonyl piperazine compound and medical application thereof | 河北省人民医院 | 2023-07-21 | — | — | CN | disclosed |
| CN-115521272-A | Benzenesulfonyl piperazine compound and medical application thereof | 河北省人民医院 | 2022-12-27 | — | — | CN | disclosed |