Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | DBH | P09172 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYBB | P04839 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.36 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30564305 | 0.82 | GAA (0.55) | GAAKDM4EDBHRECQLOPRK1 | |
| SCHEMBL22245501 | 0.82 | GAA (0.55) | GAAKDM4EDBHRECQLOPRK1 | |
| SCHEMBL17559570 | 0.82 | GAA (0.55) | GAAKDM4EDBHRECQLOPRK1 | |
| SCHEMBL11869257 | 0.81 | PTGS2 (0.36) | GAAKDM4EDBHRECQLPTGS2 | |
| SCHEMBL14098255 | 0.76 | KDM4E (0.43) | GAAKDM4EDBHRECQL | |
| SCHEMBL11858243 | 0.76 | LMNA (0.36) | PTGS2OPRK1PDE4DMAPTRAB9A | |
| SCHEMBL19253135 | 0.76 | KDM4E (0.49) | GAAKDM4EDBHRECQLMAPT | |
| SCHEMBL11863346 | 0.75 | OPRK1 (0.36) | KDM4EPTGS2OPRK1PDE4DMAPT | |
| SCHEMBL19919810 | 0.74 | KDM4E (0.55) | GAAKDM4EDBHRECQLMAPT | |
| SCHEMBL3328361 | 0.73 | MAPT (0.39) | GAAPTGS2OPRK1PDE4DMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102199119-B | Oxime ester photoinitiators | CIBA HOLDING INC | 2014-07-16 | — | — | CN | disclosed |
| US-8586268-B2 | Oxime ester photoinitiators | BASF SE (DE) | 2013-11-19 | — | — | US | disclosed |
| US-20100188765-A1 | Oxime Ester Photoinitiators | CIBA CORPORATION | 2010-07-29 | — | — | US | disclosed |
| EP-1963374-B1 | OXIME ESTER PHOTOINITIATORS | BASF SE (DE) | 2010-02-17 | — | — | EP | disclosed |
| EP-1963374-A1 | OXIME ESTER PHOTOINITIATORS | Ciba Holding Inc. (CH) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007071497-A1 | OXIME ESTER PHOTOINITIATORS | CIBA HOLDING INC. (CH) | 2007-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100188765-A1 | Oxime Ester Photoinitiators | NR2E3, CYP3A4, CHRM4 | GAA 4700/4885KDM4E 856/4885DBH 1447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.