Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | DBH | P09172 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11858243 | 0.82 | LMNA (0.36) | PTGS2OPRK1PDE4DMAPTRAB9A | |
| SCHEMBL11800787 | 0.81 | ABCC4 (0.35) | MAPTRAB9ANPC1KDM4EDBH | |
| SCHEMBL3008104 | 0.81 | GAA (0.49) | PTGS2OPRK1PDE4DMAPTRAB9A | |
| SCHEMBL11730430 | 0.76 | CTNNB1 (0.36) | MAPTRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL11863346 | 0.76 | OPRK1 (0.36) | PTGS2OPRK1PDE4DMAPTRAB9A | |
| SCHEMBL11677033 | 0.76 | MAPT (0.42) | MAPTRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL11813095 | 0.74 | GSK3B (0.44) | MAPTRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL11819107 | 0.74 | L3MBTL1 (0.38) | PDE4DMAPTRAB9ANPC1KDM4E | |
| SCHEMBL11750568 | 0.72 | L3MBTL1 (0.40) | MAPTRAB9ANPC1KDM4ELMNA | |
| SCHEMBL11553445 | 0.70 | TTR (0.39) | RAB9ANPC1KDM4EDBHGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3957988-A | Antiviral compositions containing bis-basic ketones of thioxanthene | RICHARDSON-MERRELL INC. (US) | 1976-05-18 | — | — | US | disclosed |