Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.32 |
| ▸ | HTR3A | P46098 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HRH1 | P35367 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11869257 | 0.82 | PTGS2 (0.36) | LMNAOPRK1PTGS2PDE4DHRH3 | |
| SCHEMBL11732533 | 0.80 | THRA (0.38) | POLBKMT2ABCHETP53ACHE | |
| SCHEMBL11730448 | 0.78 | L3MBTL1 (0.43) | LMNAPOLBKMT2ABCHETP53 | |
| Hydrochloric Acid SCHEMBL11734361 | 0.78 | MAOA (0.37) | LMNAPOLBKMT2ABCHETP53 | |
| SCHEMBL11866455 | 0.77 | L3MBTL1 (0.39) | KMT2ABCHETP53ADORA2AHRH3 | |
| Hydrochloric Acid SCHEMBL11862770 | 0.77 | L3MBTL1 (0.44) | LMNAPOLBKMT2ABCHETP53 | |
| SCHEMBL3008104 | 0.76 | GAA (0.49) | LMNAOPRK1KMT2APTGS2PDE4D | |
| SCHEMBL11736839 | 0.76 | PTGS2 (0.36) | OPRK1PTGS2PDE4DSLC6A3 | |
| Hydrochloric Acid SCHEMBL11859109 | 0.76 | L3MBTL1 (0.41) | LMNAKMT2ABCHETP53ADORA2A | |
| SCHEMBL11818226 | 0.76 | MAPT (0.48) | POLBOPRK1KMT2ATP53CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3957988-A | Antiviral compositions containing bis-basic ketones of thioxanthene | RICHARDSON-MERRELL INC. (US) | 1976-05-18 | — | — | US | disclosed |