Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.68 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.67 |
| ▸ | CNR1 | P21554 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL30094567 | 1.00 | EPHX2 (0.68) | EPHX2SLC6A5CNR1ALDH1A1HPGD | |
| SCHEMBL31324737 | 0.95 | DNM1 (0.72) | EPHX2SLC6A5CNR1ALDH1A1HPGD | |
| Bromide SCHEMBL30422245 | 0.93 | EPHX2 (0.60) | EPHX2SLC6A5CNR1ALDH1A1HPGD | |
| SCHEMBL5344068 | 0.92 | CNR1 (0.67) | EPHX2SLC6A5CNR1ALDH1A1HPGD | |
| SCHEMBL5344072 | 0.92 | CNR1 (0.67) | EPHX2SLC6A5CNR1ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL30094599 | 0.90 | SLC6A5 (0.60) | EPHX2SLC6A5CNR1ALDH1A1HPGD | |
| SCHEMBL30130593 | 0.90 | DNM1 (0.76) | EPHX2SLC6A5CNR1DNM1 | |
| SCHEMBL30130591 | 0.90 | DNM1 (0.76) | EPHX2SLC6A5CNR1DNM1 | |
| Bromide SCHEMBL30094755 | 0.90 | DNM1 (0.57) | EPHX2SLC6A5CNR1ALDH1A1HPGD | |
| SCHEMBL18157806 | 0.89 | EPHX2 (0.67) | EPHX2SLC6A5CNR1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11858878-B2 | Gemini surfactant composition and method for treating subterranean rock | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2024-01-02 | — | — | US | disclosed |
| US-20230132932-A1 | GEMINI SURFACTANT COMPOSITION AND METHOD FOR TREATING SUBTERRANEAN ROCK | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2023-05-04 | — | — | US | disclosed |
| US-11512045-B2 | Synthesis and evaluation of novel amido-amine cationic gemini surfactants containing flexible and rigid spacers | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2022-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230132932-A1 | GEMINI SURFACTANT COMPOSITION AND METHOD FOR TREATING SUBTERRANEAN ROCK | SGMS1, SGMS2, GEMIN4 | EPHX2 2056/4885SLC6A5 2586/4885CNR1 241/4885 |
| US-11512045-B2 | Synthesis and evaluation of novel amido-amine cationic gemini surfactants containing flexible and rigid spacers | PAM, DGKI, PHOSPHO1 | EPHX2 1910/4885SLC6A5 2200/4885CNR1 68/4885 |
| US-11858878-B2 | Gemini surfactant composition and method for treating subterranean rock | SGMS1, SGMS2, GEMIN4 | EPHX2 2056/4885SLC6A5 2586/4885CNR1 241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.