Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 6/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.32 |
| ▸ | GABRE | P78334 | 1/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.32 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16934676 | 1.00 | TERT (0.41) | TERTBCHEACHEALDH1A1TSHR | |
| SCHEMBL29935503 | 0.99 | TERT (0.40) | TERTBCHEACHEALDH1A1TSHR | |
| SCHEMBL452379 | 0.88 | TERT (0.46) | TERTALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL452116 | 0.85 | NPC1 (0.45) | TERTALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL448359 | 0.85 | NPC1 (0.45) | TERTALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL449176 | 0.85 | NPC1 (0.45) | TERTALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL451943 | 0.85 | NPC1 (0.45) | TERTALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL30096016 | 0.85 | NPC1 (0.45) | TERTALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL3521676 | 0.85 | TERT (0.42) | TERT | |
| SCHEMBL450264 | 0.85 | TERT (0.48) | TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4308107-A1 | MNTBAP AND M(III)N-SUBSTITUTED PYRIDYLPORPHYRINS(MNPS)FOR USE IN REVERSING SEPSIS-INDUCED MICROGLIAL CELLS ALTERATIONS AND/OR FOR TREATING SEPSIS OR SEPSIS-ASSOCIATED ENCEPHALOPATHY | INSTITUT PASTEUR (FR) | 2024-01-24 | — | — | EP | disclosed |
| WO-2022195100-A1 | MNTBAP AND M(III)N-SUBSTITUTED PYRIDYLPORPHYRINS(MNPS)FOR USE IN REVERSING SEPSIS-INDUCED MICROGLIAL CELLS ALTERATIONS AND/OR FOR TREATING SEPSIS OR SEPSIS-ASSOCIATED ENCEPHALOPATHY | INSTITUT PASTEUR (FR) | 2022-09-22 | — | — | WO | disclosed |