Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 6/20 | 0.48 |
| ▸ | TOP1 | P11387 | 2/20 | 0.35 |
| ▸ | CYCS | P99999 | 2/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL452379 | 0.92 | TERT (0.46) | TERTTOP1 | |
| SCHEMBL453031 | 0.90 | TERT (0.52) | TERTTOP1CYCSENPP2 | |
| SCHEMBL451943 | 0.89 | NPC1 (0.45) | TERT | |
| SCHEMBL448359 | 0.89 | NPC1 (0.45) | TERT | |
| SCHEMBL449176 | 0.89 | NPC1 (0.45) | TERT | |
| SCHEMBL30096016 | 0.89 | NPC1 (0.45) | TERT | |
| SCHEMBL452116 | 0.89 | NPC1 (0.45) | TERT | |
| SCHEMBL4914167 | 0.89 | TERT (0.51) | TERTTOP1CYCSENPP2 | |
| SCHEMBL29935687 | 0.89 | TERT (0.51) | TERTTOP1CYCSENPP2 | |
| SCHEMBL29935401 | 0.88 | NPC1 (0.44) | TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065181-A1 | METHOD OF PROVIDING NEUROPROTECTION USING SUBSTITUTED PORPHYRINS | DUKE UNIVERSITY | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065181-A1 | METHOD OF PROVIDING NEUROPROTECTION USING SUBSTITUTED PORPHYRINS | SOD1, PYGB, PSAP | TERT 4141/4885TOP1 3060/4885CYCS 40/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.