Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 6/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | TOP1 | P11387 | 1/20 | 0.33 |
| ▸ | CYCS | P99999 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL450264 | 0.87 | TERT (0.48) | TERTTOP1CYCS | |
| SCHEMBL16934676 | 0.85 | TERT (0.41) | TERT | |
| SCHEMBL30096018 | 0.85 | TERT (0.41) | TERT | |
| SCHEMBL29935503 | 0.84 | TERT (0.40) | TERT | |
| SCHEMBL452379 | 0.84 | TERT (0.46) | TERTTOP1 | |
| SCHEMBL453031 | 0.82 | TERT (0.52) | TERTTOP1CYCS | |
| SCHEMBL452116 | 0.82 | NPC1 (0.45) | TERT | |
| SCHEMBL30096016 | 0.82 | NPC1 (0.45) | TERT | |
| SCHEMBL451943 | 0.82 | NPC1 (0.45) | TERT | |
| SCHEMBL448359 | 0.82 | NPC1 (0.45) | TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8183364-B2 | Substituted porphyrins | DUKE UNIVERSITY (US) | 2012-05-22 | — | — | US | disclosed |
| US-20100305083-A1 | SUBSTITUTED PORPHYRINS | BATINIC-HABERLE INES | 2010-12-02 | — | — | US | disclosed |
| US-20100305083-A1 | SUBSTITUTED PORPHYRINS | BATINIC-HABERLE INES | 2010-12-02 | — | — | US | disclosed |
| US-7807825-B2 | Substituted porphyrins | DUKE UNIVERSITY (US) | 2010-10-05 | — | — | US | disclosed |
| US-20080021007-A1 | Substituted Porphyrins | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-01-24 | — | — | US | disclosed |
| EP-1718201-A1 | SUBSTITUTED PORPHYRINS | Duke University (US) | 2006-11-08 | — | — | EP | disclosed |
| WO-2005077269-A1 | SUBSTITUTED PORPHYRINS | DUKE UNIVERSITY (US) | 2005-08-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080021007-A1 | Substituted Porphyrins | SOD3, SOD1, PRDX3 | TERT 1529/4885ABCG2 1325/4885TOP1 3229/4885 |
| US-20100305083-A1 | SUBSTITUTED PORPHYRINS | SOD3, SOD1, PRDX3 | TERT 1424/4885ABCG2 1434/4885TOP1 3024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.