Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | ILK | Q13418 | 3/20 | 0.47 |
| ▸ | DRD2 | P14416 | 8/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PI4KA | P42356 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28849872 | 1.00 | LMNA (0.52) | LMNARAB9ANPC1SMN1; SMN2PCSK9 | |
| SCHEMBL28636881 | 0.85 | RAB9A (0.56) | RAB9ANPC1SMN1; SMN2HRH3ILK | |
| SCHEMBL30101607 | 0.78 | ILK (0.64) | LMNARAB9ANPC1SMN1; SMN2ILK | |
| SCHEMBL28849842 | 0.78 | ILK (0.64) | LMNARAB9ANPC1SMN1; SMN2ILK | |
| SCHEMBL28849853 | 0.78 | RAB9A (0.62) | RAB9ANPC1SMN1; SMN2ILKDRD2 | |
| SCHEMBL30101763 | 0.78 | RAB9A (0.62) | RAB9ANPC1SMN1; SMN2ILKDRD2 | |
| SCHEMBL30101637 | 0.75 | RAB9A (0.55) | RAB9ANPC1SMN1; SMN2ILKDRD2 | |
| SCHEMBL17747833 | 0.75 | RAB9A (0.61) | RAB9ANPC1SMN1; SMN2ILKDRD2 | |
| SCHEMBL28849859 | 0.75 | RAB9A (0.55) | RAB9ANPC1SMN1; SMN2ILKDRD2 | |
| SCHEMBL6189062 | 0.74 | ALDH1A1 (0.59) | LMNAHRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115109011-B | Benzothiazole compound, preparation method and application | 河北师范大学 | 2023-12-15 | — | — | CN | disclosed |
| CN-115109011-A | Benzothiazole compound, preparation method and application | 河北师范大学 | 2022-09-27 | — | — | CN | disclosed |