Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 11/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3413974 | 0.86 | ALDH1A1 (0.54) | ALDH1A1KDM4ETDP1TSHRGAA | |
| SCHEMBL30101817 | 0.85 | AAK1 (0.55) | AAK1ALDH1A1KDM4ETDP1KCNA5 | |
| SCHEMBL12227519 | 0.85 | KCNA5 (0.42) | AAK1KDM4EKCNA5KDM4A | |
| SCHEMBL30101803 | 0.84 | ALDH1A1 (0.48) | AAK1ALDH1A1TDP1GAAMAPT | |
| SCHEMBL20869029 | 0.84 | ALDH1A1 (0.48) | AAK1ALDH1A1TDP1GAAMAPT | |
| SCHEMBL23275515 | 0.83 | ALDH1A1 (0.50) | ALDH1A1KDM4ETDP1TSHRGAA | |
| SCHEMBL31758898 | 0.82 | DDR1 (0.45) | AAK1ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL2541437 | 0.82 | ALDH1A1 (0.42) | AAK1ALDH1A1TDP1KCNA5GAA | |
| SCHEMBL30101769 | 0.81 | LMNA (0.46) | AAK1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL8011978 | 0.81 | AAK1 (0.47) | AAK1KCNA5GAASMN1; SMN2KDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220411377-A1 | SELECTIVE NEURONAL NITRIC OXIDE SYNTHASE INHIBITORS | NORTHWESTERN UNIVERSITY | 2022-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220411377-A1 | SELECTIVE NEURONAL NITRIC OXIDE SYNTHASE INHIBITORS | NOS3, NOS1, NOS2 | AAK1 2583/4885ALDH1A1 677/4885KDM4E 3093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.