SCHEMBL3010210

SCHEMBL3010210

COc1c(C)c(C)cc(N)c1C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.40
TSHR P16473 2/20 0.40
MAPK1 P28482 1/20 0.40
ALDH1A1 P00352 6/20 0.38
TUBB4A P04350 2/20 0.37
TUBB P07437 2/20 0.37
TUBA3C P0DPH7 2/20 0.37
TUBA1B P68363 2/20 0.37
TUBA4A P68366 2/20 0.37
TUBB4B P68371 2/20 0.37
TUBB3 Q13509 2/20 0.37
TUBB2A Q13885 2/20 0.37
TUBB8 Q3ZCM7 2/20 0.37
TUBA3E Q6PEY2 2/20 0.37
TUBA1A Q71U36 2/20 0.37
TUBA1C Q9BQE3 2/20 0.37
TUBB6 Q9BUF5 2/20 0.37
TUBB2B Q9BVA1 2/20 0.37
TUBB1 Q9H4B7 2/20 0.37
ACHE P22303 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29568447 1.00 CYP3A4 (0.40) CYP3A4TSHRMAPK1ALDH1A1TUBB4A
SCHEMBL5270436 0.86 CYP3A4 (0.40) CYP3A4TSHRMAPK1ALDH1A1TUBB4A
SCHEMBL5566891 0.82 ACHE (0.43) CYP3A4MAPK1ALDH1A1TUBB1ACHE
SCHEMBL3005373 0.81 CYP3A4 (0.40) CYP3A4TSHRMAPK1ALDH1A1TUBB4A
SCHEMBL3008135 0.81 IMPDH2 (0.41) CYP3A4TSHRMAPK1ALDH1A1TUBB4A
SCHEMBL26521199 0.80 TSHR (0.41) CYP3A4TSHRMAPK1ALDH1A1TUBB4A
SCHEMBL6152570 0.79 ALDH1A1 (0.39) CYP3A4TSHRMAPK1ALDH1A1TUBB4A
SCHEMBL26113643 0.79 ACHE (0.44) CYP3A4TSHRALDH1A1TUBB4ATUBB
Hydrochloric Acid SCHEMBL8946544 0.79 IMPDH2 (0.40) CYP3A4TSHRMAPK1ALDH1A1TUBB4A
SCHEMBL30594536 0.79 ACHE (0.44) CYP3A4TSHRALDH1A1TUBB4ATUBB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9249091-B2 Post-treated sulfurized salt of an alkyl-substituted hydroxyaromatic composition CHEVRON ORONITE COMPANY LLC (US) 2016-02-02 US claimed
US-20130165359-A1 POST-TREATED SULFURIZED SALT OF AN ALKYL-SUBSTITUTED HYDROXYAROMATIC COMPOSITION CHEVRON ORONITE COMPANY LLC (US) 2013-06-27 US claimed
US-7056986-B2 ethylene monomer can be a vinyl ketone, ether, ester, halide, nitrile, aromatic, or an allyl ether; acrylic monomer can be a mono- or diacid or monoester of a diacid; a monoamine, a guanidine compound, and an aromatic diamine; improved vulcanizability, balance between processability and compression set DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2006-06-06 US claimed
US-20230322675-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH LPA RECEPTOR ACTIVITY LHOTSE BIO, INC. 2023-10-12 US disclosed
CN-110249004-B Polyimide precursor composition 东京应化工业株式会社 2022-07-19 CN disclosed
CN-108774561-B Sulfurized salts of post-treated alkyl-substituted hydroxyaromatic compositions 雪佛龙奥伦耐有限责任公司 2022-07-01 CN disclosed
CN-108389512-B Laminate, flexible device, and method for producing laminate 东京应化工业株式会社 2022-04-15 CN disclosed
CN-108387954-B Laminate, flexible device, and method for producing laminate 东京应化工业株式会社 2022-01-18 CN disclosed
US-10954340-B2 Polyimide precursor composition TOKYO OHKA KOGYO CO., LTD. (JP) 2021-03-23 US disclosed
CN-107922733-B Polyimide precursor composition 东京应化工业株式会社 2020-09-11 CN disclosed
EP-2798050-B1 POST-TREATED SULFURIZED SALT OF AN ALKYL-SUBSTITUTED HYDROXYAROMATIC COMPOSITION CHEVRON ORONITE CO (US) 2020-04-22 EP disclosed
US-9249091-B2 Post-treated sulfurized salt of an alkyl-substituted hydroxyaromatic composition CHEVRON ORONITE COMPANY LLC (US) 2016-02-02 US disclosed
EP-1449881-B1 ACRYLIC RUBBER COMPOSITION DENKI KAGAKU KOGYO KK (JP) 2014-06-18 EP disclosed
US-20130165359-A1 POST-TREATED SULFURIZED SALT OF AN ALKYL-SUBSTITUTED HYDROXYAROMATIC COMPOSITION CHEVRON ORONITE COMPANY LLC (US) 2013-06-27 US disclosed
US-8445572-B2 Rubber composition THE YOKOHAMA RUBBER CO., LTD. (JP) 2013-05-21 US disclosed
US-20100222478-A1 RUBBER COMPOSITION THE YOKOHAMA RUBBER CO., LTD (JP) 2010-09-02 US disclosed
US-20100197841-A1 HYDROXY ACID AMINE SALT, METHOD FOR PRODUCING THE SAME, AND RUBBER COMPOSITION CONTAINING THE SAME THE YOKOHAMA RUBBER CO., LTD. 2010-08-05 US disclosed
US-7056986-B2 ethylene monomer can be a vinyl ketone, ether, ester, halide, nitrile, aromatic, or an allyl ether; acrylic monomer can be a mono- or diacid or monoester of a diacid; a monoamine, a guanidine compound, and an aromatic diamine; improved vulcanizability, balance between processability and compression set DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2006-06-06 US disclosed
US-20040266922-A1 Ethylene-acrylic copolymer rubber composition DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2004-12-30 US disclosed
EP-1449881-A1 ACRYLIC RUBBER COMPOSITION DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2004-08-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230322675-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH LPA RECEPTOR ACTIVITY LPAR2, LPAR1, LPAR6 CYP3A4 4716/4885TSHR 1333/4885MAPK1 2289/4885
US-20130165359-A1 POST-TREATED SULFURIZED SALT OF AN ALKYL-SUBSTITUTED HYDROXYAROMATIC COMPOSITION TST, PAH, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 CYP3A4 2118/4885TSHR 4066/4885MAPK1 968/4885
US-20100197841-A1 HYDROXY ACID AMINE SALT, METHOD FOR PRODUCING THE SAME, AND RUBBER COMPOSITION CONTAINING THE SAME HRH3, HRH2, HRH4 CYP3A4 2805/4885TSHR 2289/4885MAPK1 1556/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.