Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL419718 | 1.00 | ALDH1A1 (0.41) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| SCHEMBL31550192 | 0.84 | ALOX15 (0.36) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| SCHEMBL8251209 | 0.83 | ALOX15 (0.39) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| SCHEMBL1104683 | 0.82 | ALDH1A1 (0.41) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| Hydrochloric Acid SCHEMBL12614768 | 0.81 | PDE2A (0.39) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| SCHEMBL19690417 | 0.79 | ALOX15 (0.33) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| SCHEMBL19225702 | 0.79 | MAPK1 (0.42) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| SCHEMBL603094 | 0.79 | VCP (0.38) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| SCHEMBL13451285 | 0.79 | TSHR (0.33) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| SCHEMBL29762963 | 0.79 | IDO1 (0.44) | MEN1KMT2ATSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4648762-A2 | PPARG MODULATORS | University of Florida Research Foundation, Incorporated (US) | 2025-11-19 | — | — | EP | disclosed |
| CN-119954793-A | Compounds as xanthine oxidase inhibitors and uses thereof | 广州市联瑞制药有限公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-115362153-B | Azaspiro compounds as monoacylglycerol lipase modulators | 詹森药业有限公司 | 2025-01-07 | — | — | CN | disclosed |
| CN-114920758-B | Luminescent material, application thereof and organic electroluminescent device comprising luminescent material | 清华大学 | 2024-09-06 | — | — | CN | disclosed |
| WO-2024151519-A2 | PPARG MODULATORS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATIN, INCORPORATED (US) | 2024-07-18 | — | — | WO | disclosed |
| US-20230096641-A1 | HPK1 ANTAGONISTS AND USES THEREOF | NIMBUS DISCOVERY, INC. | 2023-03-30 | — | — | US | disclosed |
| EP-4126852-A1 | AZASPIROCYCLES AS MONOACYLGLYCEROL LIPASE MODULATORS | Janssen Pharmaceutica NV (BE) | 2023-02-08 | — | — | EP | disclosed |
| CN-115362153-A | Aza spiro rings as monoacylglycerol lipase modulators | 詹森药业有限公司 | 2022-11-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230096641-A1 | HPK1 ANTAGONISTS AND USES THEREOF | PDXK, HIPK1, PCK1 | ALDH1A1 4740/4885ALOX15 3810/4885HSD17B10 603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.