Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 6/20 | 0.50 |
| ▸ | BRD4 | O60885 | 13/20 | 0.42 |
| ▸ | GNRHR | P30968 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30104792 | 0.83 | ADORA3 (0.39) | STING1BRD4 | |
| SCHEMBL29153650 | 0.83 | MTNR1A (0.42) | STING1 | |
| Hydrochloric Acid SCHEMBL30104853 | 0.81 | JAK2 (0.44) | — | |
| SCHEMBL16150685 | 0.80 | MAPT (0.47) | BRD4 | |
| SCHEMBL27341116 | 0.79 | HPGD (0.43) | STING1BRD4 | |
| SCHEMBL20141699 | 0.79 | MTNR1A (0.59) | CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL27311582 | 0.79 | BRD4 (0.40) | STING1BRD4 | |
| SCHEMBL15563812 | 0.79 | DRD2 (0.44) | BRD4 | |
| SCHEMBL16151412 | 0.78 | GAA (0.43) | — | |
| SCHEMBL24187458 | 0.77 | MTNR1A (0.46) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396485-A | PARP7 inhibitors | 轩竹生物科技股份有限公司 | 2024-01-12 | — | — | CN | disclosed |
| WO-2022247839-A1 | PARP7 INHIBITOR | 山东轩竹医药科技有限公司 | 2022-12-01 | — | — | WO | disclosed |