Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.49 |
| ▸ | FEN1 | P39748 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | USP5 | P45974 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426211 | 0.81 | TRPA1 (0.54) | ERCC5FEN1HRH3POLBUSP5 | |
| SCHEMBL27909990 | 0.79 | L3MBTL1 (0.59) | ERCC5FEN1HRH3POLBGSK3B | |
| SCHEMBL16552727 | 0.74 | GSK3B (0.70) | ERCC5FEN1GSK3BHSD11B1MAPT | |
| SCHEMBL9172112 | 0.73 | GSK3B (0.48) | ERCC5FEN1HRH3GSK3BHSD11B1 | |
| SCHEMBL21542529 | 0.73 | L3MBTL1 (0.45) | ERCC5FEN1HRH3POLBUSP5 | |
| SCHEMBL9719602 | 0.73 | GSK3B (0.55) | ERCC5FEN1HRH3GSK3BHSD11B1 | |
| SCHEMBL8306301 | 0.73 | POLB (0.64) | ERCC5FEN1POLBGSK3BMAPT | |
| SCHEMBL9124420 | 0.71 | POLB (0.54) | ERCC5FEN1POLBGSK3BMAPT | |
| SCHEMBL392858 | 0.71 | NR4A2 (0.65) | ERCC5FEN1USP5GSK3BHSD11B1 | |
| SCHEMBL28372673 | 0.71 | L3MBTL1 (0.72) | ERCC5FEN1GSK3BHSD11B1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8431609-B2 | Process for preparation of pyrazole derivatives | SHAH DARMESH MAHENDRABHAI (IN) | 2013-04-30 | — | — | US | disclosed |
| US-20100190988-A1 | PROCESS FOR PREPARATION OF PYRAZOLE DERIVATIVES | SHAH DARMESH MAHENDRABHAI | 2010-07-29 | — | — | US | disclosed |
| WO-2008102367-A1 | PROCESS FOR PREPARATION OF PYRAZOLE DERIVATIVES | SHAH DARMESH MAHENDRABHAI (IN) | 2008-08-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190988-A1 | PROCESS FOR PREPARATION OF PYRAZOLE DERIVATIVES | PDXK, PYCR1, PPOX | ERCC5 4296/4885FEN1 2425/4885HRH3 2598/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.