Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATG4B | Q9Y4P1 | 12/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 10/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3007866 | 1.00 | ATG4B (0.42) | ATG4BPLA2G1BTHRATHRBCYP1A2 | |
| SCHEMBL3008493 | 1.00 | ATG4B (0.42) | ATG4BPLA2G1BTHRATHRBCYP1A2 | |
| SCHEMBL3008390 | 0.99 | KDM4E (0.41) | ATG4BPLA2G1BTHRATHRBCYP1A2 | |
| SCHEMBL3010718 | 0.94 | KDM4E (0.37) | ATG4BPLA2G1BTHRATHRBCYP1A2 | |
| SCHEMBL3001217 | 0.88 | KDM4E (0.39) | KDM4ENPC1ALDH1A1HPGDCASP3 | |
| SCHEMBL2998701 | 0.82 | KDM4E (0.41) | KDM4EALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL651213 | 0.77 | GPR84 (0.41) | ALDH1A1HPGDGPR84 | |
| Hydrochloric Acid SCHEMBL12468552 | 0.76 | GPR84 (0.40) | ALDH1A1HPGDGPR84 | |
| SCHEMBL10766106 | 0.76 | ALDH1A1 (0.41) | ALDH1A1HPGDGPR84 | |
| SCHEMBL1082482 | 0.76 | HCAR2 (0.50) | CYP1A2TDP1KDM4EALDH1A1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100197752-A1 | UROCANIC ACID DERIVATIVES USEFUL FOR THE TREATMENT OF IMMUNE-RELATED AND INFLAMMATORY DISEASES | VALLETTA HEALTH IP EE B.V. (NL) | 2010-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197752-A1 | UROCANIC ACID DERIVATIVES USEFUL FOR THE TREATMENT OF IMMUNE-RELATED AND INFLAMMATORY DISEASES | UTS2R, UACA, HCAR1 | ATG4B 4447/4885PLA2G1B 1679/4885THRA 2209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.