Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | JAK2 | O60674 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | STAT3 | P40763 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21621272 | 1.00 | ALDH1A1 (0.58) | ALDH1A1KDM4EHSD17B10MAPTRAB9A | |
| SCHEMBL2199524 | 0.78 | PTGS2 (0.38) | ALDH1A1KDM4EHSD17B10MAPTRAB9A | |
| SCHEMBL28345474 | 0.77 | KDM4E (0.39) | ALDH1A1KDM4EHSD17B10MAPTRAB9A | |
| SCHEMBL5022932 | 0.77 | MAPT (0.65) | ALDH1A1KDM4EHSD17B10MAPTRAB9A | |
| SCHEMBL30209584 | 0.77 | KDM4E (0.39) | ALDH1A1KDM4EHSD17B10MAPTRAB9A | |
| SCHEMBL4056111 | 0.76 | ADORA2B (0.65) | ALDH1A1KDM4EHSD17B10MAPTRAB9A | |
| SCHEMBL2199521 | 0.75 | GRM4 (0.59) | ALDH1A1KDM4EHSD17B10MAPTRAB9A | |
| SCHEMBL4447801 | 0.75 | BPTF (0.54) | ALDH1A1KDM4EHSD17B10RAB9AHPGD | |
| SCHEMBL23998422 | 0.74 | ALDH1A1 (0.48) | ALDH1A1KDM4EHSD17B10MAPTRAB9A | |
| SCHEMBL5361055 | 0.73 | KDM4E (0.52) | ALDH1A1KDM4EHSD17B10RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022203399-A1 | ADENOSINE A2A RECEPTOR ANTAGONIST AND USE THEREOF | 주식회사 스탠다임 | 2022-09-29 | — | — | WO | disclosed |