Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 4/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.31 |
| ▸ | LIMK2 | P53671 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30108003 | 0.88 | MET (0.40) | METNPSR1TDP1MAPTALDH1A1 | |
| SCHEMBL30107975 | 0.78 | L3MBTL1 (0.40) | PDE2APDE10AL3MBTL1TDP1KDM4E | |
| SCHEMBL30107973 | 0.76 | KDM4E (0.46) | METTDP1KDM4EMAPTALDH1A1 | |
| SCHEMBL30107988 | 0.73 | TSHR (0.33) | L3MBTL1KDM4ETSHRSMN1; SMN2 | |
| SCHEMBL30108036 | 0.73 | PIM1 (0.46) | NPSR1PDE2APDE10AL3MBTL1TDP1 | |
| SCHEMBL30108065 | 0.72 | TSHR (0.47) | PDE10AKDM4EMAPTALDH1A1TSHR | |
| SCHEMBL30107968 | 0.71 | IDH1 (0.35) | PDE2APDE10AL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL30108027 | 0.69 | TSHR (0.39) | KDM4EALDH1A1TSHRSMN1; SMN2RAB9A | |
| SCHEMBL30107966 | 0.68 | TSHR (0.40) | PDE2APDE10AL3MBTL1TDP1KDM4E | |
| SCHEMBL4590708 | 0.66 | L3MBTL1 (0.48) | NPSR1L3MBTL1KDM4EMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022203399-A1 | ADENOSINE A2A RECEPTOR ANTAGONIST AND USE THEREOF | 주식회사 스탠다임 | 2022-09-29 | — | — | WO | disclosed |