Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 2/20 | 0.35 |
| ▸ | PDE2A | O00408 | 6/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CASR | P41180 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30107976 | 0.88 | ROCK1 (0.34) | IDH1PDE2APDE10AHTR3AALDH1A1 | |
| SCHEMBL30107975 | 0.79 | L3MBTL1 (0.40) | PDE2APDE10AL3MBTL1ALDH1A1POLB | |
| SCHEMBL30108036 | 0.76 | PIM1 (0.46) | PDE2APDE10AL3MBTL1ALDH1A1POLB | |
| SCHEMBL30107973 | 0.72 | KDM4E (0.46) | ALDH1A1POLBHTTNPC1RAB9A | |
| SCHEMBL30107957 | 0.72 | HRH4 (0.32) | PDE10AL3MBTL1NPC1 | |
| SCHEMBL30107965 | 0.71 | MET (0.40) | PDE2APDE10AL3MBTL1ALDH1A1POLB | |
| SCHEMBL30107966 | 0.68 | TSHR (0.40) | PDE2APDE10AL3MBTL1ALDH1A1POLB | |
| SCHEMBL30107953 | 0.67 | GAA (0.41) | L3MBTL1POLBHTTNPC1RAB9A | |
| SCHEMBL4590708 | 0.66 | L3MBTL1 (0.48) | L3MBTL1POLBNPC1RAB9AMAPK6 | |
| SCHEMBL30108038 | 0.65 | PIM1 (0.46) | ALDH1A1POLBHTTPIM1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022203399-A1 | ADENOSINE A2A RECEPTOR ANTAGONIST AND USE THEREOF | 주식회사 스탠다임 | 2022-09-29 | — | — | WO | disclosed |