Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | POLB | P06746 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30107966 | 0.85 | TSHR (0.40) | MAPTLMNATSHRHSD17B10TDP1 | |
| SCHEMBL30108037 | 0.78 | TRPC5 (0.37) | MAPTLMNATSHRHSD17B10TDP1 | |
| SCHEMBL30107949 | 0.75 | HTT (0.34) | MAPTLMNATSHRHSD17B10TDP1 | |
| SCHEMBL30108047 | 0.74 | RAB9A (0.39) | MAPTHSD17B10ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL30108060 | 0.73 | MAPT (0.38) | MAPTLMNATSHRHSD17B10TDP1 | |
| SCHEMBL30107975 | 0.72 | L3MBTL1 (0.40) | LMNATSHRTDP1ALDH1A1POLB | |
| SCHEMBL30108036 | 0.67 | PIM1 (0.46) | MAPTHSD17B10TDP1ALDH1A1POLB | |
| SCHEMBL30108038 | 0.67 | PIM1 (0.46) | LMNAHSD17B10ALDH1A1POLBHTT | |
| SCHEMBL19848194 | 0.67 | NPC1 (0.60) | MAPTLMNATSHRALDH1A1POLB | |
| SCHEMBL19848195 | 0.66 | ALDH1A1 (0.45) | MAPTLMNATSHRTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022203399-A1 | ADENOSINE A2A RECEPTOR ANTAGONIST AND USE THEREOF | 주식회사 스탠다임 | 2022-09-29 | — | — | WO | disclosed |