Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.59 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL11738819 | 0.96 | GSK3B (0.59) | GSK3BHDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL8987897 | 0.94 | SMN1; SMN2 (0.68) | GSK3BHDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL11780135 | 0.90 | GSK3B (0.57) | GSK3BHDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL9342342 | 0.88 | GSK3B (0.52) | GSK3BHDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL6142684 | 0.88 | SRD5A2 (0.53) | GSK3BHDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL8051337 | 0.87 | SMN1; SMN2 (0.70) | GSK3BSMN1; SMN2L3MBTL1MAPTHTT | |
| Pyridine SCHEMBL28895312 | 0.85 | MAPT (0.53) | GSK3BHDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL21202169 | 0.83 | GSK3B (0.55) | GSK3BHDAC1HDAC3HDAC2HDAC8 | |
| Ethyne SCHEMBL8050785 | 0.82 | SMN1; SMN2 (0.64) | GSK3BSMN1; SMN2L3MBTL1MAPTHTT | |
| SCHEMBL2116189 | 0.82 | HSD17B3 (0.67) | GSK3BHDAC1HDAC3HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 877 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114956932-A | Synthesis method of polysubstituted chiral tetrahydroquinoline compound | 东北大学秦皇岛分校 | 2022-08-30 | — | — | CN | claimed |
| CN-110092724-A | A kind of preparation method of N, N- dimethyl-1-naphthylamine class compound | 湖南大学 | 2019-08-06 | — | — | CN | claimed |
| CN-106831784-B | The method of one pot of tandem reaction synthesis tryptamines ketone alkaloid | 河南师范大学 | 2019-07-19 | — | — | CN | claimed |
| WO-2019062561-A1 | SYNTHESIS METHODS OF FIROCOXIB AND INTERMEDIATE THEREOF | SICHUAN QINGMU PHARMACEUTICAL CO., LTD. (CN) | 2019-04-04 | — | — | WO | claimed |
| CN-106083686-B | The method of alpha-brominated acetophenone oxime ether synthesis 2,4- diaryl pyrrole class compound | 苏州大学 | 2019-01-22 | — | — | CN | claimed |
| CN-105924325-B | A kind of preparation method of 6,6,12,12- tetramethyl -6,12- dihydro indeno [1,2-b] fluorenes | 东阳市天齐知识产权运营有限公司 | 2018-11-30 | — | — | CN | claimed |
| CN-106083810-A | A kind of preparation method of polysubstituted thiochromanone derivant | 青岛科技大学 | 2016-11-09 | — | — | CN | claimed |
| CN-106008137-A | Preparation method of 6,6,12,12-tetramethyl-6,12-dihydroindeno[1,2-b] fluorene | 李金铃 | 2016-10-12 | — | — | CN | claimed |
| CN-105924325-A | Preparation method of 6,6,12,12-tetramethyl-6,12-dihydro indeno [1,2-b] fluorene | 李金铃 | 2016-09-07 | — | — | CN | claimed |
| CN-105017012-A | Acetoxylation method of benzyl groups | UNIV JIANGXI NORMAL | 2015-11-04 | — | — | CN | claimed |
| CN-104803816-A | Preparation method of carboxylic ester | UNIV EAST CHINA NORMAL | 2015-07-29 | — | — | CN | claimed |
| CN-104508116-A | Pesticidal flavobacterium strains and bioactive compositions, metabolites and uses | MARRONE BIO INNOVATIONS INC | 2015-04-08 | — | — | CN | claimed |
| CN-104177298-A | 4, 4-disubstituted-4, 5-dihydro-1H-imidazole-5-one and derivatives thereof as well as synthesis method thereof | UNIV XIANGTAN | 2014-12-03 | — | — | CN | claimed |
| CN-102341494-B | Transaminase polypeptides | CODEXIS, INC. (US) | 2014-10-15 | — | — | CN | claimed |
| CN-102341494-A | TRANSAMINASE POLYPEPTIDES | CODEXIS INC | 2012-02-01 | — | — | CN | claimed |
| US-20060287397-A1 | Dl-hydroxy-alkyl-phenylamides having anticonvulsive activity | MEZA TOLEDO SERGIO E | 2006-12-21 | — | — | US | claimed |
| CN-1103781-A | Use of phenalkylamines | HOFFMANN LA ROCHE (CH) | 1995-06-21 | — | — | CN | claimed |
| US-3956153-A | MINIMIZATION OF UNDERCOOLING | BIO-MEDICAL SCIENCES, INC. (US) | 1976-05-11 | — | — | US | claimed |
| US-20260028600-A1 | TRANSAMINASE POLYPEPTIDES | CODEXIS INC (US) | 2026-01-29 | — | — | US | disclosed |
| US-3933895-A | PROSTAGLANDINS, ANTIULCER, ANTICOAGULANTS, NASAL PATENCY, LABOR INDUCERS, WOUND HEALING | THE UPJOHN COMPANY (US) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060287397-A1 | Dl-hydroxy-alkyl-phenylamides having anticonvulsive activity | GABRB2, HRH3, HRH4 | GSK3B 2241/4885HDAC1 1038/4885HDAC3 311/4885 |
| US-20260028600-A1 | TRANSAMINASE POLYPEPTIDES | GOT1, OAT, PEPD | GSK3B 1701/4885HDAC1 4268/4885HDAC3 4193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.