SCHEMBL301118

SCHEMBL301118

CC(CC(F)(F)F)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GABRR1 P24046 2/20 0.42
CYP1A2 P05177 1/20 0.42
FOLH1 Q04609 2/20 0.37
NAALAD2 Q9Y3Q0 2/20 0.37
ENPEP Q07075 2/20 0.37
BLM P54132 1/20 0.37
TP53 P04637 1/20 0.36
ACE2 Q9BYF1 1/20 0.34
LTA4H P09960 1/20 0.33
ALDH1A1 P00352 1/20 0.32
RNPEP Q9H4A4 1/20 0.32
SLC7A5 Q01650 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12885928 1.00 GABRR1 (0.42) GABRR1CYP1A2FOLH1NAALAD2ENPEP
SCHEMBL5960707 1.00 GABRR1 (0.42) GABRR1CYP1A2FOLH1NAALAD2ENPEP
Pyridine SCHEMBL28275234 0.84 TBXAS1 (0.39) GABRR1CYP1A2ALDH1A1
SCHEMBL10266069 0.82 GABRR1 (0.41) GABRR1CYP1A2FOLH1NAALAD2ENPEP
SCHEMBL19918461 0.82 GABRR1 (0.41) GABRR1CYP1A2FOLH1NAALAD2ENPEP
SCHEMBL15905686 0.82 GABRR1 (0.41) GABRR1CYP1A2FOLH1NAALAD2ENPEP
SCHEMBL9438162 0.80 GABRR1 (0.39) GABRR1CYP1A2FOLH1NAALAD2ENPEP
SCHEMBL1766737 0.80 GABRR1 (0.39) GABRR1CYP1A2FOLH1NAALAD2ENPEP
SCHEMBL27335599 0.80 GABRR1 (0.39) GABRR1CYP1A2FOLH1NAALAD2ENPEP
SCHEMBL14281509 0.79 ALDH1A1 (0.32) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 208 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117441254-A Electrolyte for secondary battery, and electronic device 宁德新能源科技有限公司 2024-01-23 CN claimed
CN-116706232-A Electrolyte of secondary battery, secondary battery and electronic device 宁德新能源科技有限公司 2023-09-05 CN claimed
EP-2212964-B1 NON-AQUEOUS ELECTROLYTE LITHIUM SECONDARY BATTERY LG CHEMICAL LTD (KR) 2017-06-21 EP claimed
EP-2304837-B1 CYLINDRICAL LITHIUM SECONDARY BATTERY LG CHEMICAL LTD (KR) 2017-01-04 EP claimed
EP-2238643-B1 POUCH-TYPE LITHIUM SECONDARY BATTERY LG CHEMICAL LTD (KR) 2014-03-26 EP claimed
EP-2266159-B1 NON-AQUEOUS ELECTROLYTE SOLUTION FOR LITHIUM SECONDARY BATTERY AND LITHIUM SECONDARY BATTERY COMPRISING THE SAME LG CHEMICAL LTD (KR) 2013-10-23 EP claimed
EP-1377589-B1 OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS PHARMACIA ITALIA SPA (IT) 2005-09-07 EP claimed
EP-0489548-B1 A process for the preparation of 2(R)-methyl-4,4,4-trifluorobutylamine, intermediates, and a process for the preparation of a derivative thereof ZENECA LTD (GB) 1994-12-14 EP claimed
US-5274118-A Process for preparing (2R)-methyl-4,4,4-trifluorobutylamine IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-12-28 US claimed
EP-0489548-A1 A process for the preparation of 2(R)-methyl-4,4,4-trifluorobutylamine, intermediates, and a process for the preparation of a derivative thereof ZENECA LIMITED (GB) 1992-06-10 EP claimed
JP-4290870-A None JP disclosed
EP-4747245-A1 PHARMACEUTICAL COMPOUNDS Almac Discovery Limited (GB) 2026-05-27 EP disclosed
US-20260103459-A1 SUBSTITUTED AZACYLES AS TRPM8 MODULATORS GIVAUDAN SA (CH) 2026-04-16 US disclosed
US-12528801-B2 Substituted azacyles as TRPM8 modulators GIVAUDAN SA (CH) 2026-01-20 US disclosed
US-12466805-B2 Pharmaceutical compounds ALMAC DISCOVERY LIMITED (GB) 2025-11-11 US disclosed
JP-H04290870-A PRODUCTION METHOD IMPERIAL CHEM IND PLC <ICI> 1992-10-15 JP disclosed
EP-0489548-A1 A process for the preparation of 2(R)-methyl-4,4,4-trifluorobutylamine, intermediates, and a process for the preparation of a derivative thereof ZENECA LIMITED (GB) 1992-06-10 EP disclosed
EP-0489548-A1 A process for the preparation of 2(R)-methyl-4,4,4-trifluorobutylamine, intermediates, and a process for the preparation of a derivative thereof ZENECA LIMITED (GB) 1992-06-10 EP disclosed
EP-0489547-A1 A process for the preparation of a 3-alkylated indole, intermediates, and a process for the preparation of a derivative thereof ZENECA LIMITED (GB) 1992-06-10 EP disclosed
EP-0432984-A2 Carbamoyl derivatives ZENECA LIMITED (GB) 1991-06-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260103459-A1 SUBSTITUTED AZACYLES AS TRPM8 MODULATORS TRPM8, TRPM7, TRPM5 GABRR1 1235/4885CYP1A2 1434/4885FOLH1 4696/4885
US-12466805-B2 Pharmaceutical compounds USP19, USP18, UBE2I GABRR1 2775/4885CYP1A2 805/4885FOLH1 603/4885
US-12528801-B2 Substituted azacyles as TRPM8 modulators TRPM8, TRPM7, TRPM4 GABRR1 1286/4885CYP1A2 1702/4885FOLH1 4590/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.