Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | CES1 | P23141 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | GSK3B | P49841 | 2/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.58 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.56 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9838448 | 0.86 | SMN1; SMN2 (0.64) | MAPTHPGDKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL446368 | 0.80 | MAPT (0.64) | MAPK1MAPTTDP1KMT2ACES1 | |
| Dibenzoylmethane SCHEMBL21800928 | 0.79 | KMT2A (0.90) | MAPK1MAPTTDP1KMT2ACES1 | |
| Dibenzoylmethane SCHEMBL21800927 | 0.79 | KMT2A (0.90) | MAPK1MAPTTDP1KMT2ACES1 | |
| Dibenzoylmethane SCHEMBL10356288 | 0.78 | MEN1 (1.00) | MAPK1MAPTTDP1KMT2ACES1 | |
| SCHEMBL719034 | 0.78 | NR4A2 (0.85) | MAPK1MAPTTDP1KMT2ACES1 | |
| Dibenzoylmethane SCHEMBL39582 | 0.78 | MEN1 (1.00) | MAPK1MAPTTDP1KMT2ACES1 | |
| SCHEMBL30121738 | 0.78 | NR4A2 (0.85) | MAPK1MAPTTDP1KMT2ACES1 | |
| Dibenzoylmethane SCHEMBL1704711 | 0.78 | MEN1 (1.00) | MAPK1MAPTTDP1KMT2ACES1 | |
| SCHEMBL7429718 | 0.77 | NPC1 (0.60) | MAPTTDP1CYP3A4HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 949 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3929207-B1 | PEPTIDE FTTFTVT FOR USE IN TREATING FIBROSIS | UNIV TEXAS (US) | 2024-07-17 | — | — | EP | claimed |
| EP-3929207-A1 | INHIBITION OF PULMONARY FIBROSIS WITH NUTLIN-3A AND PEPTIDES | Board of Regents, The University of Texas System (US) | 2021-12-29 | — | — | EP | claimed |
| WO-2021158573-A1 | METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES | Natural Extraction Systems, LLC (US) | 2021-08-12 | — | — | WO | claimed |
| US-20190330192-A1 | SUBSTITUTED AZOLYLPYRROLONES AND AZOLYLHYDANTOINS AND SALTS THEREOF AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES | BAYER AKTIENGESELLSCHAFT (DE) | 2019-10-31 | — | — | US | claimed |
| EP-3558976-A1 | SUBSTITUTED AZOLYLPYRROLONES AND AZOLYLHYDANTOINES AND SALTS THEREOF AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES | Bayer CropScience Aktiengesellschaft (DE) | 2019-10-30 | — | — | EP | claimed |
| CN-110128897-A | A kind of crosslinking with radiation cured flame-retardant coating and preparation method thereof | 湖南辰砾新材料有限公司 | 2019-08-16 | — | — | CN | claimed |
| CN-107686456-B | A kind of quinolione key intermediate ethyl ester aminate and its preparation method and application | 杭州师范大学 | 2018-10-23 | — | — | CN | claimed |
| WO-2018114663-A1 | SUBSTITUTED AZOLYLPYRROLONES AND AZOLYLHYDANTOINES AND SALTS THEREOF AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-06-28 | — | — | WO | claimed |
| US-20180086791-A1 | INHIBITION OF PULMONARY FIBROSIS WITH NUTLIN-3A AND PEPTIDES | UNIV TEXAS (US) | 2018-03-29 | — | — | US | claimed |
| EP-2200440-B1 | ANTIBACTERIAL AMIDE AND SULFONAMIDE SUBSTITUTED HETEROCYCLIC UREA COMPOUNDS | CRESTONE INC (US) | 2017-07-19 | — | — | EP | claimed |
| US-4472403-A | Quinoline derivatives and pharmaceutical compositions and methods for treating cardiovascular disease with such compounds | A.C.F. CHEMIEFARMA N.V. (NL) | 1984-09-18 | — | — | US | claimed |
| EP-0045161-B1 | AMIDES OF 4-OXO-5-AMIDOHEXANOIC ACID DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-03-14 | — | — | EP | claimed |
| US-4413000-A | BACTERICIDES | BEECHAM GROUP LIMITED (GB) | 1983-11-01 | — | — | US | claimed |
| EP-0079740-A1 | Anthraniloyloxyalkanoates | RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) | 1983-05-25 | — | — | EP | claimed |
| EP-0053017-A1 | Amide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-06-02 | — | — | EP | claimed |
| EP-0045161-A1 | Amides of 4-oxo-5-amidohexanoic acid derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-02-03 | — | — | EP | claimed |
| EP-0039903-A2 | 8-Substituted pyrrolizidines and quaternary ammonium salts thereof | SUNTORY KABUSHIKI KAISHA (JP) | 1981-11-18 | — | — | EP | claimed |
| EP-0030044-A1 | Quinoline derivatives, processes for their preparation, their use, pharmaceutical compositions containing them and a method for the preparation of these pharmaceutical compositions | ACF CHEMIEFARMA NV (NL) | 1981-06-10 | — | — | EP | claimed |
| US-4018930-A | ANALGESICS, SEDATIVES, TRANQUILIZERS | ENDO LABORATORIES, INC. (US) | 1977-04-19 | — | — | US | claimed |
| US-3932429-A | Novel azabicyclo octane derivative and process for preparing same | TANABE SEIYAKU CO., LTD (JA) | 1976-01-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180086791-A1 | INHIBITION OF PULMONARY FIBROSIS WITH NUTLIN-3A AND PEPTIDES | IGFBP4, FN1, MDM2 | MAPK1 2010/4885MAPT 1857/4885TDP1 1236/4885 |
| US-20190330192-A1 | SUBSTITUTED AZOLYLPYRROLONES AND AZOLYLHYDANTOINS AND SALTS THEREOF AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES | AGPS, AASDHPPT, HPD | MAPK1 2372/4885MAPT 4075/4885TDP1 2971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.