Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23803823 | 1.00 | KMT2A (0.37) | KMT2AALDH1A1NPC1RAB9AALOX15 | |
| SCHEMBL23803875 | 0.83 | NPC1 (0.40) | KMT2AALDH1A1NPC1RAB9AALOX15 | |
| SCHEMBL30152297 | 0.83 | NPC1 (0.40) | KMT2AALDH1A1NPC1RAB9AALOX15 | |
| SCHEMBL15310836 | 0.71 | KMT2A (0.43) | KMT2AALDH1A1NPC1RAB9AALOX15 | |
| SCHEMBL30120818 | 0.71 | GPR52 (0.42) | KMT2AALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23803908 | 0.71 | GPR52 (0.42) | KMT2AALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30152262 | 0.71 | GPR52 (0.42) | KMT2AALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL26659396 | 0.71 | NPSR1 (0.47) | KMT2AALDH1A1NPC1RAB9ANPSR1 | |
| SCHEMBL17980321 | 0.70 | NPC1 (0.49) | KMT2AALDH1A1NPC1RAB9ANPSR1 | |
| SCHEMBL15051243 | 0.69 | ALDH1A1 (0.36) | KMT2AALDH1A1NPC1RAB9AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115515681-B | GPR52 modulator compounds | 奈克斯拉制药英国有限公司 | 2024-09-03 | — | — | CN | disclosed |
| EP-4117784-A1 | GPR52 MODULATOR COMPOUNDS | Heptares Therapeutics Limited (GB) | 2023-01-18 | — | — | EP | disclosed |
| CN-115515681-A | GPR52 modulator compounds | 赫普泰雅治疗有限公司 | 2022-12-23 | — | — | CN | disclosed |