Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 4/20 | 0.43 |
| ▸ | MMP9 | P14780 | 4/20 | 0.43 |
| ▸ | MMP3 | P08254 | 2/20 | 0.43 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 3/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL264568 | 0.90 | MMP2 (0.43) | MMP2MMP9MMP3MMP13MMP8 | |
| SCHEMBL264852 | 0.89 | MMP2 (0.54) | MMP2MMP9MMP3MMP13MMP8 | |
| SCHEMBL13889220 | 0.84 | MMP2 (0.40) | MMP2MMP9MMP3MMP13MMP8 | |
| SCHEMBL265249 | 0.83 | MMP2 (0.40) | MMP2MMP9MMP3MMP13MMP8 | |
| SCHEMBL300822 | 0.82 | MMP2 (0.53) | MMP2MMP9MMP3MMP13MMP8 | |
| SCHEMBL265305 | 0.82 | LMNA (0.36) | MMP2MMP9MMP3MMP13MMP8 | |
| SCHEMBL271537 | 0.80 | MMP2 (0.51) | MMP2MMP9MMP3MMP13MMP8 | |
| SCHEMBL264182 | 0.80 | ALDH1A1 (0.48) | MMP2MMP9MMP3MMP13MMP8 | |
| SCHEMBL265660 | 0.79 | MMP2 (0.41) | MMP2MMP9MMP3MMP13MMP8 | |
| SCHEMBL9301436 | 0.79 | SMN1; SMN2 (0.45) | ALDH1A1SMN1; SMN2NAMPTHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8133743-B2 | Phenobarbital derivatives useful in immunoassay | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2012-03-13 | — | — | US | disclosed |