Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.47 |
| ▸ | USP7 | Q93009 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GRK2 | P25098 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30128619 | 0.90 | GRK2 (0.52) | TRPA1PSMB2MAPTKMT2AGRK2 | |
| SCHEMBL28389854 | 0.81 | SMN1; SMN2 (0.53) | LMNAGRK2SMN1; SMN2RAB9APOLB | |
| SCHEMBL30128609 | 0.77 | GRK2 (0.49) | HDAC6APPHDAC1HDAC2HDAC11 | |
| SCHEMBL30128600 | 0.77 | TRPA1 (0.52) | TRPA1LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL30128680 | 0.77 | MCL1 (0.50) | HDAC6APPHDAC1HDAC2HDAC11 | |
| SCHEMBL30129021 | 0.77 | GRK2 (0.49) | HDAC6APPHDAC1HDAC2HDAC11 | |
| SCHEMBL10659297 | 0.77 | CYP1A2 (0.50) | SMN1; SMN2 | |
| SCHEMBL29025443 | 0.76 | PDE5A (0.50) | PDE5AUSP7HDAC6MAPTLMNA | |
| SCHEMBL20864351 | 0.75 | USP7 (0.85) | USP7 | |
| SCHEMBL6225210 | 0.75 | SLC2A1 (0.52) | PDE5ATRPA1PSMB2HDAC6APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116552-B | Quinazolinone compound and preparation method thereof | 河北科技大学 | 2022-10-11 | — | — | CN | disclosed |