Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | P2RX3 | P56373 | 8/20 | 0.50 |
| ▸ | GRK2 | P25098 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30129021 | 0.85 | GRK2 (0.49) | P2RX3GRK2 | |
| SCHEMBL30128619 | 0.85 | GRK2 (0.52) | TRPA1P2RX3GRK2KMT2A | |
| SCHEMBL30128680 | 0.85 | MCL1 (0.50) | P2RX3GRK2NPSR1LMNAL3MBTL1 | |
| SCHEMBL30128609 | 0.85 | GRK2 (0.49) | P2RX3GRK2KDM4E | |
| SCHEMBL30128753 | 0.84 | P2RX3 (0.61) | P2RX3ALDH1A1KDM4EHPGD | |
| SCHEMBL28389854 | 0.81 | SMN1; SMN2 (0.53) | GRK2LMNATP53CYP1A2CYP3A4 | |
| SCHEMBL10084695 | 0.81 | TP53 (0.51) | TRPA1NPSR1ALDH1A1MEN1LMNA | |
| SCHEMBL30128668 | 0.81 | L3MBTL1 (0.58) | P2RX3GRK2ALDH1A1MEN1LMNA | |
| SCHEMBL12049203 | 0.78 | TP53 (0.53) | TRPA1NPSR1ALDH1A1MEN1LMNA | |
| SCHEMBL30128824 | 0.77 | PDE5A (0.51) | TRPA1GRK2ALDH1A1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116552-B | Quinazolinone compound and preparation method thereof | 河北科技大学 | 2022-10-11 | — | — | CN | disclosed |