Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRK2 | P25098 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | P2RX3 | P56373 | 7/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | ALPG | P10696 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.42 |
| ▸ | EIF4EBP1 | Q13541 | 1/20 | 0.42 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30129021 | 0.85 | GRK2 (0.49) | GRK2P2RX3APPHDAC1HDAC2 | |
| SCHEMBL30128600 | 0.85 | TRPA1 (0.52) | GRK2KDM4EP2RX3 | |
| SCHEMBL30128680 | 0.85 | MCL1 (0.50) | GRK2P2RX3APPHDAC1HDAC2 | |
| SCHEMBL30128619 | 0.85 | GRK2 (0.52) | GRK2P2RX3MMP13CASR | |
| SCHEMBL30128753 | 0.81 | P2RX3 (0.61) | KDM4EP2RX3 | |
| SCHEMBL28389854 | 0.81 | SMN1; SMN2 (0.53) | GRK2 | |
| SCHEMBL30128668 | 0.81 | L3MBTL1 (0.58) | GRK2P2RX3 | |
| SCHEMBL3314021 | 0.79 | MEN1 (0.45) | GRK2P2RX3ALPLALPGMMP13 | |
| SCHEMBL30128824 | 0.77 | PDE5A (0.51) | GRK2EIF4EBP1APPHDAC1HDAC2 | |
| SCHEMBL2828446 | 0.76 | CASR (0.47) | GRK2P2RX3ALPLALPGMMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116552-B | Quinazolinone compound and preparation method thereof | 河北科技大学 | 2022-10-11 | — | — | CN | disclosed |