Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA5A | P35218 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 2/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| P-Xylene SCHEMBL2990077 | 0.89 | CA2 (0.50) | CA2CA1CA5ACA9GAA | |
| Trifluoromethanesulfonic Acid SCHEMBL28750655 | 0.89 | CA1 (0.43) | CA2CA1CA9MMP1MMP2 | |
| SCHEMBL3914557 | 0.82 | CA2 (0.36) | CA2CA1CA5ACA9RAPGEF4 | |
| P-Cresol SCHEMBL28538740 | 0.81 | ACHE (0.56) | CA2CA1CA5ACA9RAPGEF4 | |
| Trifluoromethanesulfonic Acid SCHEMBL1516187 | 0.80 | ALDH1A1 (0.42) | CA2CA1CA9ALDH1A1HDAC1 | |
| Trifluoromethanesulfonic Acid SCHEMBL30131107 | 0.79 | RAPGEF4 (0.45) | CA2CA1RAPGEF4MMP1MMP2 | |
| Trifluoromethanesulfonic Acid SCHEMBL3686060 | 0.79 | TRPV1 (0.51) | CA2CA1CA9KMT2ACA12 | |
| Trifluoromethanesulfonic Acid SCHEMBL6248784 | 0.79 | CA2 (0.42) | CA2CA1CA5ACA9GAA | |
| Trifluoromethanesulfonic Acid SCHEMBL485503 | 0.79 | ALDH1A1 (0.49) | CA2CA1CA5ACA9GAA | |
| Trifluoromethanesulfonic Acid SCHEMBL2123096 | 0.79 | ALDH1A1 (0.49) | CA2CA1CA5ACA9GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010066357-A1 | BENZOTHIAZOLE AMIDES FOR DETECTION OF AMYLOID BETA | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-06-17 | — | — | WO | disclosed |